Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690478 | 0.86 | CA2 (0.30) | — | |
| SCHEMBL6693673 | 0.85 | ALDH1A1 (0.41) | ALDH1A1KDM4EKMT2AMEN1GAA | |
| SCHEMBL6689539 | 0.84 | IDO1 (0.36) | ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL5059322 | 0.65 | TDP2 (0.40) | ALDH1A1KDM4EKMT2AMEN1GAA | |
| SCHEMBL6692386 | 0.63 | USP2 (0.36) | ALDH1A1KDM4EKMT2AMEN1GAA | |
| SCHEMBL4386782 | 0.62 | ALDH1A1 (0.40) | ALDH1A1KDM4EKMT2AMEN1GAA | |
| SCHEMBL10746773 | 0.62 | ALDH1A1 (0.40) | ALDH1A1KDM4EKMT2AMEN1GAA | |
| SCHEMBL10733504 | 0.61 | ALDH1A1 (0.37) | ALDH1A1KDM4EKMT2AMEN1GAA | |
| SCHEMBL31704076 | 0.61 | ALDH1A1 (0.40) | ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL2743830 | 0.60 | ALDH1A1 (0.47) | ALDH1A1KDM4EKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004101584-A1 | MACROLIDES SUBSTITUTED AT THE 3-POSITION HAVING ANTIMICROBIAL ACTIVITY | GLAXO GROUP LIMITED (GB) | 2004-11-25 | — | — | WO | disclosed |