Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4385104 | 0.69 | BRD4 (0.38) | USP2ALDH1A1GAATSHRMEN1 | |
| SCHEMBL9667378 | 0.64 | CASP3 (0.48) | USP2ALDH1A1GAAKDM4ETSHR | |
| SCHEMBL6692389 | 0.63 | ALDH1A1 (0.35) | ALDH1A1GAAKDM4ETSHRTDP1 | |
| SCHEMBL5868634 | 0.62 | PARK7 (0.36) | USP2ALDH1A1GAAKDM4ETSHR | |
| SCHEMBL9667216 | 0.61 | KMT2A (0.46) | USP2ALDH1A1GAAKDM4ETSHR | |
| SCHEMBL9667758 | 0.61 | USP2 (0.43) | USP2ALDH1A1GAAKDM4ETSHR | |
| SCHEMBL9666290 | 0.60 | USP2 (0.42) | USP2ALDH1A1GAAKDM4ETSHR | |
| SCHEMBL9668245 | 0.60 | USP2 (0.42) | USP2ALDH1A1GAAKDM4ETSHR | |
| SCHEMBL4399700 | 0.60 | ALDH1A1 (0.38) | ALDH1A1GAAKDM4ESMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL443786 | 0.59 | LOXL2 (0.54) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004101584-A1 | MACROLIDES SUBSTITUTED AT THE 3-POSITION HAVING ANTIMICROBIAL ACTIVITY | GLAXO GROUP LIMITED (GB) | 2004-11-25 | — | — | WO | disclosed |