Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27572461 | 0.86 | RAB9A (0.45) | MAPTRECQLMTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL1895641 | 0.82 | TAAR1 (0.58) | — | |
| SCHEMBL9462243 | 0.77 | HPGD (0.56) | RECQLTSHR | |
| SCHEMBL7998297 | 0.76 | RAB9A (0.60) | MAPTRECQLMTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL9662599 | 0.75 | SMN1; SMN2 (0.52) | MAPT | |
| SCHEMBL10639479 | 0.73 | OPRM1 (0.51) | MTNR1AMTNR1B | |
| SCHEMBL8744545 | 0.73 | NAAA (0.47) | MTNR1AMTNR1B | |
| SCHEMBL30344909 | 0.73 | ALDH1A1 (0.49) | MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL577685 | 0.73 | CES2 (0.44) | MAPTRECQLMTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL733157 | 0.72 | LMNA (0.71) | MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |