SCHEMBL6693933

SCHEMBL6693933

C=CCC(C)C(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.49
PGR P06401 1/20 0.47
ADRA2A P08913 1/20 0.47
ADRA2B P18089 1/20 0.47
HTR2A P28223 1/20 0.47
HRH1 P35367 1/20 0.47
KCNH2 Q12809 1/20 0.47
MMP1 P03956 1/20 0.47
MMP2 P08253 1/20 0.47
MMP3 P08254 1/20 0.47
MMP7 P09237 1/20 0.47
LMNA P02545 9/20 0.45
ALDH1A1 P00352 5/20 0.45
MAPT P10636 3/20 0.45
ATM Q13315 2/20 0.45
NPC1 O15118 1/20 0.45
MAPK1 P28482 1/20 0.45
HTT P42858 1/20 0.45
RAB9A P51151 1/20 0.45
AKT1 P31749 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14498572 1.00 CYP2C19 (0.49) CYP2C19PGRADRA2AADRA2BHTR2A
SCHEMBL10644287 0.83 PGR (0.49) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL6258236 0.81 PGR (0.47) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL3143553 0.81 CYP2C19 (0.52) CYP2C19PGRADRA2AADRA2BHTR2A
SCHEMBL10975235 0.81 MDM2 (0.55) CYP2C19PGRADRA2AADRA2BHTR2A
SCHEMBL8737261 0.80 CYP2C19 (0.71) CYP2C19MMP1MMP2MMP3MMP7
SCHEMBL9356364 0.79 CYP2C19 (0.55) CYP2C19PGRADRA2AADRA2BHTR2A
SCHEMBL2405032 0.79 CYP2C19 (0.50) CYP2C19PGRADRA2AADRA2BHTR2A
SCHEMBL6834266 0.79 MDM2 (0.49) CYP2C19PGRADRA2AADRA2BHTR2A
SCHEMBL31492931 0.79 ATM (0.50) CYP2C19PGRADRA2AADRA2BHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61205225-A None JP disclosed
EP-4426684-B1 CYCLIC ACETALS AND KETALS FOR THE LIGHT-INDUCED RELEASE OF ACTIVE ALDEHYDES AND KETONES FIRMENICH & CIE (CH) 2025-09-17 EP disclosed
US-20250042871-A1 CYCLIC ACETALS AND KETALS FOR THE LIGHT-INDUCED RELEASE OF ACTIVE ALDEHYDES AND KETONES FIRMENICH & CIE (CH) 2025-02-06 US disclosed
EP-4426684-A1 CYCLIC ACETALS AND KETALS FOR THE LIGHT-INDUCED RELEASE OF ACTIVE ALDEHYDES AND KETONES Firmenich SA (CH) 2024-09-11 EP disclosed
CN-118215656-A Cyclic acetals and ketals for photoinduction-released active aldehydes and ketones 弗门尼舍有限公司 2024-06-18 CN disclosed
WO-2023078909-A1 CYCLIC ACETALS AND KETALS FOR THE LIGHT-INDUCED RELEASE OF ACTIVE ALDEHYDES AND KETONES FIRMENICH SA (CH) 2023-05-11 WO disclosed
US-20230076320-A1 NORFENFLURAMINE TO TREAT DRAVET SYNDROME ZOGENIX INTERNATIONAL LIMITED (GB) 2023-03-09 US disclosed
CN-114686195-A High-temperature-resistant corrosion inhibitor for oil field water injection well and preparation method thereof 中国石油化工股份有限公司 2022-07-01 CN disclosed
US-20200297665-A1 COMPOSITIONS AND METHODS FOR TREATING SEIZURE DISORDERS ZOGENIX INTERNATIONAL LIMITED (GB) 2020-09-24 US disclosed
EP-3518908-A2 COMPOSITIONS AND METHODS FOR TREATING SEIZURE DISORDERS Zogenix International Limited (GB) 2019-08-07 EP disclosed
WO-2018060732-A2 COMPOSITIONS AND METHODS FOR TREATING SEIZURE DISORDERS ZOGENIX INTERNATIONAL LIMITED (GB) 2018-04-05 WO disclosed
US-20180092864-A1 COMPOSITIONS AND METHODS FOR TREATING SEIZURE DISORDERS ZOGENIX INTERNATIONAL LIMITED (GB) 2018-04-05 US disclosed
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0850948-B1 Propiophenone derivatives and process for preparing the same TANABE SEIYAKU CO (JP) 2002-04-24 EP disclosed
US-6048842-A ANTIDIABETIC AGENT TANABE SEIYAKU CO., LTD. (JP) 2000-04-11 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed
EP-0850948-A1 Propiophenone derivatives and process for preparing the same TANABE SEIYAKU CO., LTD. (JP) 1998-07-01 EP disclosed
JP-S61205225-A PRODUCTION OF KETONE MITSUBISHI CHEM IND LTD 1986-09-11 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230076320-A1 NORFENFLURAMINE TO TREAT DRAVET SYNDROME TPH2, HTR5A, TPH1 CYP2C19 348/4885PGR 4471/4885ADRA2A 201/4885
US-20180092864-A1 COMPOSITIONS AND METHODS FOR TREATING SEIZURE DISORDERS PSEN2, EPM2A, TPH2 CYP2C19 227/4885PGR 3626/4885ADRA2A 462/4885
US-20200297665-A1 COMPOSITIONS AND METHODS FOR TREATING SEIZURE DISORDERS PSEN2, EPM2A, TPH2 CYP2C19 227/4885PGR 3626/4885ADRA2A 462/4885
US-20250042871-A1 CYCLIC ACETALS AND KETALS FOR THE LIGHT-INDUCED RELEASE OF ACTIVE ALDEHYDES AND KETONES PKM, PKLR, AKR1C1 CYP2C19 219/4885PGR 3153/4885ADRA2A 1130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.