Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.49 |
| ▸ | CTSL | P07711 | 7/20 | 0.49 |
| ▸ | CTSB | P07858 | 7/20 | 0.49 |
| ▸ | CTSH | P09668 | 5/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696441 | 0.97 | CTSK (0.46) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL6653241 | 0.97 | CTSK (0.46) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL6062499 | 0.91 | CTSS (0.47) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL6632644 | 0.91 | CTSS (0.47) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL6062906 | 0.90 | HSD11B1 (0.43) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL6063838 | 0.79 | CTSS (0.44) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL6694046 | 0.79 | CTSK (0.53) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL6688702 | 0.79 | CTSK (0.53) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL6061604 | 0.79 | CTSK (0.50) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL6061600 | 0.79 | CTSK (0.50) | CTSKCTSLCTSBCTSHCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142999-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2004-07-22 | — | — | US | claimed |
| US-20040142999-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142999-A1 | Novel compounds and compositions as cathepsin inhibitors | CTSS, CTSB, CTSE | CTSK 8/4885CTSL 11/4885CTSB 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.