Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593099 | 0.87 | KMO (0.44) | AURKARPS6KB1TP53MEN1KMT2A | |
| SCHEMBL28496853 | 0.80 | AURKA (0.51) | AURKARPS6KB1PARP1TP53ALDH1A1 | |
| SCHEMBL17979907 | 0.78 | ALDH1A1 (0.58) | AURKARPS6KB1PARP1ALDH1A1KDM4E | |
| SCHEMBL4714644 | 0.75 | FAAH (0.50) | AURKARPS6KB1PARP1TP53HSD17B10 | |
| SCHEMBL25302480 | 0.75 | KDM4E (0.47) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL28020044 | 0.72 | CYP1A2 (0.50) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL325422 | 0.71 | NPC1 (0.70) | AURKARPS6KB1PARP1MEN1KMT2A | |
| SCHEMBL29410870 | 0.71 | NPC1 (0.70) | AURKARPS6KB1PARP1MEN1KMT2A | |
| SCHEMBL29482199 | 0.71 | CNR1 (0.58) | TP53MEN1KMT2AALDH1A1HTT | |
| SCHEMBL4994306 | 0.70 | ALDH1A1 (0.54) | TP53ALDH1A1KDM4EHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110745-A1 | Therapeutic chroman compounds | INTEL CORPORATION | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110745-A1 | Therapeutic chroman compounds | HTR1A, ACHE, CALCA | AURKA 1556/4885RPS6KB1 1798/4885PARP1 3361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.