Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 4/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | PNLIP | P16233 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683423 | 0.88 | MAPT (0.48) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL6698055 | 0.85 | ALDH1A1 (0.42) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL6689991 | 0.85 | MAPT (0.41) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL6691606 | 0.83 | HSD17B2 (0.41) | MEN1MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6689149 | 0.81 | GPR139 (0.39) | ANO1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL6678578 | 0.79 | MAPT (0.42) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL6679654 | 0.78 | TRPM8 (0.45) | MEN1MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL23623288 | 0.68 | KMT2A (0.47) | KCNK3KCNK9RXFP1MEN1MAPT | |
| SCHEMBL31457366 | 0.68 | KMT2A (0.47) | KCNK3KCNK9RXFP1MEN1MAPT | |
| SCHEMBL23623239 | 0.67 | HPGD (0.41) | KCNK3KCNK9RXFP1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |