Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677935 | 0.88 | KCNK3 (0.40) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6698055 | 0.86 | ALDH1A1 (0.42) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6689149 | 0.83 | GPR139 (0.39) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6678578 | 0.82 | MAPT (0.42) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6691606 | 0.79 | HSD17B2 (0.41) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6689991 | 0.76 | MAPT (0.41) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL22340596 | 0.75 | ALDH1A1 (0.75) | KMT2AHPGDALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6679654 | 0.74 | TRPM8 (0.45) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL4916663 | 0.70 | FGFR2 (0.37) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6677495 | 0.69 | SMN1; SMN2 (0.48) | MAPTMEN1KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |