SCHEMBL6700601

SCHEMBL6700601

N#Cc1cc(F)c(N=C=O)cc1Oc1ccc2ccccc2c1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.43
FNTB P49356 1/20 0.43
PGGT1B P53609 1/20 0.43
PLA2G7 Q13093 1/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
AR P10275 12/20 0.38
GAA P10253 1/20 0.38
RCE1 Q9Y256 1/20 0.38
CYP19A1 P11511 1/20 0.37
BCAT2 O15382 1/20 0.36
BCAT1 P54687 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6833317 0.87 BCAT2 (0.46) FNTAFNTBPGGT1BPLA2G7MEN1
SCHEMBL8194251 0.82 POLB (0.47) FNTAFNTBPGGT1BARGAA
SCHEMBL6694769 0.78 GAA (0.53) FNTAFNTBPGGT1BPLA2G7MEN1
SCHEMBL8485509 0.76 GAA (0.51) MEN1NPC1RAB9AKMT2ACA1
SCHEMBL7021135 0.72 SLC22A12 (0.40) ARGAABCAT2BCAT1
SCHEMBL8132627 0.71 GAA (0.62) FNTAFNTBPGGT1BPLA2G7MEN1
SCHEMBL6594425 0.70 TRPV4 (0.47) AR
SCHEMBL6690921 0.69 NLRP3 (0.46) FNTAFNTBPGGT1BPLA2G7MEN1
SCHEMBL20510954 0.69 ALDH1A1 (0.57) FNTAFNTBPGGT1BPLA2G7MEN1
SCHEMBL30360773 0.69 ALDH1A1 (0.57) FNTAFNTBPGGT1BPLA2G7MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040029735-A1 Substituted herbicidal phenyluracils ANDREE ROLAND (DE) 2004-02-12 US disclosed
US-6624120-B1 Such as 1-(4-cyano-2-fluoro-5-(6-methoxy-naphthalen-2-yl-oxy)-phenyl)-2,6-dioxo -1,2,3,6-tetrahydro-pyrimidine-4-carboxylic acid BAYER AKTIENGESELLSCHAFT (DE) 2003-09-23 US disclosed
EP-1192140-A1 SUBSTITUTED HERBICIDAL PHENYLURACILS Bayer Aktiengesellschaft (DE) 2002-04-03 EP disclosed
WO-2000078734-A1 SUBSTITUTED HERBICIDAL PHENYLURACILS BAYER AKTIENGESELLSCHAFT (DE) 2000-12-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040029735-A1 Substituted herbicidal phenyluracils DDT, MTX1, MTX2 FNTA 2427/4885FNTB 1181/4885PGGT1B 1323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.