Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.36 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.35 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021990 | 0.85 | SLC22A12 (0.36) | SLC22A12ARBCAT2BCAT1SLC6A2 | |
| SCHEMBL7021511 | 0.78 | HPGD (0.53) | POLBGAAPIN1 | |
| SCHEMBL7025384 | 0.78 | SLC22A12 (0.41) | SLC22A12EZH2POLBGAAAR | |
| SCHEMBL6833317 | 0.75 | BCAT2 (0.46) | POLBGAAARERBB2BCAT2 | |
| SCHEMBL6281807 | 0.74 | ALDH1A1 (0.39) | SLC22A12GAA | |
| SCHEMBL6242836 | 0.72 | PPOX (0.43) | GAA | |
| SCHEMBL7003782 | 0.72 | ALDH1A1 (0.47) | POLBGAA | |
| SCHEMBL8926445 | 0.72 | NPC1 (0.43) | — | |
| SCHEMBL6700601 | 0.72 | FNTA (0.43) | GAAARBCAT2BCAT1 | |
| SCHEMBL8998063 | 0.70 | TDP1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973395-B1 | DIARYL ETHERS AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM | ISK AMERICAS INC (US) | 2003-12-03 | — | — | EP | disclosed |
| US-6479435-B1 | OR DIARYL SULFIDES, 1-(4-CHLORO-2-FLUORO-5-(2-PYRIMIDYLOXY)PHENYL)-4-DIFLUOROMETHY L-3-METHYL-1,4-DIHYDRO-1,2,4-TRIAZOLIN-5-ONE FOR EXAMPLE | ISK AMERICAS INCORPORATED | 2002-11-12 | — | — | US | disclosed |
| US-20020161224-A1 | Diaryl ethers and processes for their preparation and herbicidal and desiccant compositions containing them | PULMAN DAVID A (US) | 2002-10-31 | — | — | US | disclosed |
| US-6333296-B1 | FOR CONTRILLING WEEDS | ISK AMERICAS INCORPORATED | 2001-12-25 | — | — | US | disclosed |
| US-6303543-B1 | Diaryl ethers and processes for their preparation and herbicidal and desiccant compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2001-10-16 | — | — | US | disclosed |
| EP-0973395-A4 | DIARYL ETHERS AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM | ISK AMERICAS INC (US) | 2001-10-04 | — | — | EP | disclosed |
| US-6121201-A | HETEROARYL SUBSTITUTED HALO-PYRAZOLE SUBSTITUTED DIARYL ETHERS OR THIOETHERS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2000-09-19 | — | — | US | disclosed |
| EP-0973395-A1 | DIARYL ETHERS AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM | ISK Americas Incorporated (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998041093-A1 | DIARYL ETHERS AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM | ISK AMERICAS INCORPORATED (US) | 1998-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161224-A1 | Diaryl ethers and processes for their preparation and herbicidal and desiccant compositions containing them | HDHD5, DDT, CBR3 | SLC22A12 4361/4885EZH2 2707/4885POLB 2894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.