Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.49 |
| ▸ | KCND2 | Q9NZV8 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL670518 | 1.00 | SLC6A4 (0.50) | SLC6A4KCNA5SCN5AKCND2MEN1 | |
| SCHEMBL670425 | 1.00 | SLC6A4 (0.50) | SLC6A4KCNA5SCN5AKCND2MEN1 | |
| SCHEMBL17851251 | 0.89 | CYP3A4 (0.48) | SLC6A4KCNA5SCN5AKCND2MEN1 | |
| SCHEMBL23008446 | 0.85 | MAPT (0.46) | MEN1KMT2AEPHX1ALDH1A1USP2 | |
| SCHEMBL13214223 | 0.84 | SLC6A4 (0.50) | SLC6A4KCNA5SCN5AKCND2MEN1 | |
| SCHEMBL12810343 | 0.81 | SLC6A4 (0.50) | SLC6A4KCNA5SCN5AKCND2MEN1 | |
| SCHEMBL2632456 | 0.79 | SLC6A4 (0.55) | SLC6A4KCNA5SCN5AKCND2MEN1 | |
| SCHEMBL31497113 | 0.78 | CA1 (0.53) | MEN1KMT2AEPHX1ALDH1A1POLB | |
| SCHEMBL31497114 | 0.78 | CA1 (0.53) | MEN1KMT2AEPHX1ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL1762230 | 0.78 | KCNA5 (0.56) | SLC6A4KCNA5SCN5AKCND2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2605772-B1 | PROCESS FOR PREPARING AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME INTERNAT AG (CH) | 2016-06-22 | — | — | EP | claimed |
| EP-2606139-B1 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF (1R,2R)-2-(3,4-DIMETHOXYPHENETHOXY)CYCLOHEXANAMINE | CODEXIS INC (US) | 2015-07-15 | — | — | EP | claimed |
| US-9006460-B2 | Process for preparing aminocyclohexyl ether compounds | CARDIOME INTERNATIONAL AG (CH) | 2015-04-14 | — | — | US | claimed |
| US-8932836-B2 | Biocatalysts and methods for the synthesis of (1R,2R)-2-(3,4-dimethoxyphenethoxy)cyclohexanamine | CODEXIS, INC. (US) | 2015-01-13 | — | — | US | claimed |
| US-20130164794-A1 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF (1R,2R)-2-(3,4-DIMETHOXYPHENETHOXY)CYCLOHEXAMINE | CODEXIS, INC. (US) | 2013-06-27 | — | — | US | claimed |
| EP-2605772-A2 | PROCESS FOR PREPARING AMINOCYCLOHEXYL ETHER COMPOUNDS | Merck Sharp & Dohme Corp. (US) | 2013-06-26 | — | — | EP | claimed |
| EP-2606139-A2 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF (1R,2R)-2-(3,4-DIMETHOXYPHENETHOXY)CYCLOHEXANAMINE | Codexis, Inc. (US) | 2013-06-26 | — | — | EP | claimed |
| US-20130149751-A1 | PROCESS FOR PREPARING AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME INTERNATIONAL SA (CH) | 2013-06-13 | — | — | US | claimed |
| WO-2012024100-A2 | PROCESS FOR PREPARING AMINOCYCLOHEXYL ETHER COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2012-02-23 | — | — | WO | claimed |
| WO-2012024104-A2 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF (1R,2R)-2-(3,4-DIMETHOXYPHENETHOXY)CYCLOHEXANAMINE | CODEXIS, INC. (US) | 2012-02-23 | — | — | WO | claimed |
| US-20250388940-A1 | ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION OF KETONE AND AMINE COMPOUNDS | CODEXIS, INC. (US) | 2025-12-25 | — | — | US | disclosed |
| US-12421532-B2 | Polynucleotides encoding engineered imine reductases | CODEXIS, INC. (US) | 2025-09-23 | — | — | US | disclosed |
| EP-4577644-A1 | BIOCATALYSTS AND METHODS THEREOF | Tesaro, Inc. (US) | 2025-07-02 | — | — | EP | disclosed |
| US-20250101389-A1 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF SUBSTITUTED LACTAMS | CODEXIS INC (US) | 2025-03-27 | — | — | US | disclosed |
| US-12163162-B2 | Biocatalysts and methods for the synthesis of substituted lactams | CODEXIS, INC. (US) | 2024-12-10 | — | — | US | disclosed |
| WO-2012024104-A2 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF (1R,2R)-2-(3,4-DIMETHOXYPHENETHOXY)CYCLOHEXANAMINE | CODEXIS, INC. (US) | 2012-02-23 | — | — | WO | disclosed |
| WO-2012024100-A2 | PROCESS FOR PREPARING AMINOCYCLOHEXYL ETHER COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2012-02-23 | — | — | WO | disclosed |
| WO-2012024100-A2 | PROCESS FOR PREPARING AMINOCYCLOHEXYL ETHER COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2012-02-23 | — | — | WO | disclosed |
| WO-2012024104-A2 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF (1R,2R)-2-(3,4-DIMETHOXYPHENETHOXY)CYCLOHEXANAMINE | CODEXIS, INC. (US) | 2012-02-23 | — | — | WO | disclosed |
| US-20100152464-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250101389-A1 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF SUBSTITUTED LACTAMS | BCAT1, GOT1, OAT | SLC6A4 1955/4885KCNA5 4797/4885SCN5A 4236/4885 |
| US-20250388940-A1 | ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION OF KETONE AND AMINE COMPOUNDS | DCXR, PDXK, XDH | SLC6A4 3054/4885KCNA5 1208/4885SCN5A 1485/4885 |
| US-20100152464-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | DDC, PAICS, CYP4F2 | SLC6A4 2113/4885KCNA5 3600/4885SCN5A 3852/4885 |
| US-12163162-B2 | Biocatalysts and methods for the synthesis of substituted lactams | BCAT1, GOT1, OAT | SLC6A4 1955/4885KCNA5 4797/4885SCN5A 4236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.