Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.42 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | RORB | Q92753 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4203346 | 0.84 | MTTP (0.52) | CFTRPDK2TRPV1 | |
| SCHEMBL6705895 | 0.84 | CFTR (0.48) | MRGPRX4CFTRSLC6A4SLC6A3ADAMTS7 | |
| SCHEMBL6697416 | 0.83 | ITGB1 (0.49) | MRGPRX4CFTRSLC6A4SLC6A3ADAMTS7 | |
| SCHEMBL7642362 | 0.82 | SLC6A4 (0.49) | CFTRSLC6A4SLC6A3NR4A2 | |
| SCHEMBL5099992 | 0.82 | FABP4 (0.49) | MRGPRX4ADAMTS7KCNJ5KCNJ3RORC | |
| SCHEMBL7638449 | 0.82 | FABP4 (0.55) | CFTRSLC6A4SLC6A3KDM4ENR4A2 | |
| SCHEMBL6704771 | 0.81 | CFTR (0.45) | MRGPRX4CFTRSLC6A4SLC6A3PDK2 | |
| SCHEMBL6706499 | 0.80 | ALDH1A1 (0.48) | SLC6A4SLC6A3KDM4ENR4A2 | |
| SCHEMBL6798068 | 0.79 | P2RX1 (0.46) | CFTRPDK2TRPV1P2RX1 | |
| SCHEMBL29979725 | 0.77 | SLC6A3 (0.69) | CFTRSLC6A4SLC6A3PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040024215-A1 | Benzamide derivatives and their use as apob-100 and mtp inhibitors | SMITHKLINE BEECHAM CORPORATION | 2004-02-05 | — | — | US | disclosed |
| EP-1289971-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS APOB-100 AND MTP INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001092241-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS APOB-100 AND MTP INHIBITORS | GLAXO GROUP LIMITED (GB) | 2001-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040024215-A1 | Benzamide derivatives and their use as apob-100 and mtp inhibitors | APOB, APOL1, CETP | MRGPRX4 1792/4885CFTR 1451/4885SLC6A4 4113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.