Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115058 | 0.94 | ACHE (0.42) | RAB9ANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL6705304 | 0.79 | ACHE (0.35) | TSHRACHEMAPTALDH1A1 | |
| SCHEMBL5779452 | 0.77 | ACHE (0.44) | RAB9ANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL183516 | 0.76 | ALDH1A1 (0.35) | RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL6969894 | 0.76 | HSD17B1 (0.50) | ALDH1A1 | |
| SCHEMBL5217872 | 0.75 | ACHE (0.50) | RAB9AACHECNR2CNR1L3MBTL1 | |
| SCHEMBL26567 | 0.75 | MAOA (0.41) | ALDH1A1MEN1KMT2AATM | |
| SCHEMBL589437 | 0.75 | MAOA (0.41) | ALDH1A1MEN1KMT2AATM | |
| SCHEMBL67548 | 0.72 | ACHE (0.38) | RAB9ANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL27889021 | 0.72 | ACHE (0.42) | RAB9ANPC1SMN1; SMN2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104254525-A | Aromatic ring compound | TAKEDA PHARMACEUTICAL | 2014-12-31 | — | — | CN | disclosed |