Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9403927 | 0.86 | KDM4E (0.51) | TLR8LMNAMEN1NR1I2CHRM2 | |
| SCHEMBL27644486 | 0.82 | KDM4E (0.41) | TLR8LMNAMEN1NR1I2CHRM2 | |
| SCHEMBL9408817 | 0.82 | TLR8 (0.43) | TLR8LMNAMEN1NR1I2CHRM2 | |
| SCHEMBL9869771 | 0.82 | KDM4E (0.41) | TLR8LMNAMEN1NR1I2CHRM2 | |
| SCHEMBL295413 | 0.82 | LMNA (0.40) | TLR8LMNAMEN1NR1I2CHRM2 | |
| SCHEMBL27888042 | 0.81 | ALDH1A1 (0.41) | LMNACYP3A4MAPTKDM4ENPC1 | |
| SCHEMBL5921968 | 0.81 | LMNA (0.43) | TLR8LMNAMEN1NR1I2CHRM2 | |
| SCHEMBL4468026 | 0.78 | ALOX5 (0.48) | TLR8LMNACYP3A4MAPTKDM4E | |
| SCHEMBL27503559 | 0.78 | ALOX5 (0.43) | TLR8LMNAKDM4ENPC1RAB9A | |
| SCHEMBL4957643 | 0.78 | MEN1 (0.56) | LMNAMEN1NR1I2CHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020065341-A1 | Benzotriazole UV absorbers having enhanced durability | RAVICHANDRAN RAMANATHAN (US) | 2002-05-30 | — | — | US | claimed |
| US-20040138452-A1 | Long chain hindered amines and compositions stabilized therewith | WOOD MERVIN G (US) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138452-A1 | Long chain hindered amines and compositions stabilized therewith | TYR, DDC, AOC2 | TLR8 2211/4885LMNA 1113/4885MEN1 2859/4885 |
| US-20020065341-A1 | Benzotriazole UV absorbers having enhanced durability | TERT, AHR, ARNT | TLR8 2175/4885LMNA 2749/4885MEN1 4490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.