Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710267 | 0.92 | RXFP1 (0.34) | RORCKDM4EALDH1A1 | |
| SCHEMBL6710232 | 0.90 | NTRK1 (0.34) | RORCLMNA | |
| SCHEMBL6707799 | 0.87 | RORC (0.35) | RORCGRM5KDM4EPOLBMAPT | |
| SCHEMBL6712257 | 0.84 | ALDH1A1 (0.36) | RORCKDM4ESMN1; SMN2POLBUSP2 | |
| SCHEMBL6711396 | 0.81 | HSD11B1 (0.38) | GRM5HSD11B1KDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL6710388 | 0.81 | L3MBTL1 (0.38) | RORCKDM4ESMN1; SMN2POLBALDH1A1 | |
| SCHEMBL6708003 | 0.79 | KMT2A (0.32) | RORCKDM4EALDH1A1MAPTTP53 | |
| SCHEMBL6710089 | 0.77 | NTRK1 (0.33) | RORCKDM4EALDH1A1LMNA | |
| SCHEMBL6710049 | 0.76 | HIF1A (0.39) | KDM4ESMN1; SMN2ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL6830370 | 0.76 | LMNA (0.36) | RORCKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | RORC 1202/4885GRM5 4139/4885HSD11B1 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.