SCHEMBL6709652

SCHEMBL6709652

O=C(O)c1c(Sc2ccccc2)c2cc(Cl)ccc2n1Cc1ccc(Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
CYP3A4 P08684 1/20 1.00
MAPT P10636 1/20 1.00
ALOX15 P16050 1/20 1.00
TSHR P16473 1/20 1.00
ALOX12 P18054 1/20 1.00
PPARG P37231 1/20 1.00
RECQL P46063 1/20 1.00
BLM P54132 1/20 1.00
HSD17B10 Q99714 1/20 1.00
EDNRB P24530 6/20 0.56
EDNRA P25101 6/20 0.56
PTGDR2 Q9Y5Y4 6/20 0.55
KDM4E B2RXH2 1/20 0.54
USP2 O75604 1/20 0.54
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.54
POLB P06746 1/20 0.54
AKR1B1 P15121 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21465521 0.96 MEN1 (0.93) MEN1KMT2ACYP3A4MAPTALOX15
SCHEMBL29465029 0.96 MEN1 (0.93) MEN1KMT2ACYP3A4MAPTALOX15
SCHEMBL21465631 0.95 MEN1 (0.91) MEN1KMT2ACYP3A4MAPTALOX15
SCHEMBL25761849 0.93 MEN1 (0.87) MEN1KMT2ACYP3A4MAPTALOX15
SCHEMBL21465481 0.92 MAPT (0.85) MEN1KMT2ACYP3A4MAPTALOX15
SCHEMBL21465486 0.91 MEN1 (0.83) MEN1KMT2ACYP3A4MAPTALOX15
SCHEMBL25761854 0.91 MEN1 (0.83) MEN1KMT2ACYP3A4MAPTALOX15
SCHEMBL21465553 0.91 MEN1 (0.83) MEN1KMT2ACYP3A4MAPTALOX15
SCHEMBL21465466 0.91 MEN1 (0.83) MEN1KMT2ACYP3A4MAPTALOX15
SCHEMBL21465533 0.90 MEN1 (0.82) MEN1KMT2ACYP3A4MAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3452041-B1 COMPOSITIONS AND METHODS FOR ADMINISTERING PPAR-GAMMA-AGONISTS, SURFACTANT PEPTIDES AND PHOSPHOLIPIDS LOS ANGELES BIOMEDICAL RES INST HARBOR UCLA MEDICAL CT (US) 2026-01-14 EP claimed
US-12337023-B2 Methods and compositions for the prevention and treatment of disease STEALTH BIOTHERAPEUTICS INC. (US) 2025-06-24 US claimed
US-20240398905-A1 COMPOSITIONS AND METHOD FOR ADMINISTERING PPARgamma AGONISTS, SURFACTANT PEPTIDES AND PHOSOPHOLIPIDS LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER 2024-12-05 US claimed
US-11951158-B2 Compositions and methods for administering PPARγ agonists, surfactant peptides and phospholipids LINDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER (US) 2024-04-09 US claimed
US-20230172919-A1 AN INSULIN SENSITIZER FOR USE IN THE PREVENTION AND/OR TREATMENT OF THE DAMAGES CAUSED BY RETINAL DETACHMENT SORBONNE UNIVERSITE (FR) 2023-06-08 US claimed
US-20230043587-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DISEASE STEALTH BIOTHERAPEUTICS INC. (US) 2023-02-09 US claimed
EP-4125838-A1 AN INSULIN SENSITIZER FOR USE IN THE PREVENTION AND/OR TREATMENT OF THE DAMAGES CAUSED BY RETINAL DETACHMENT SORBONNE UNIVERSITE (FR) 2023-02-08 EP claimed
US-20220324796-A1 ANTIBIOTIC COMPOUNDS EMORY UNIVERSITY 2022-10-13 US claimed
US-20220142985-A1 AGENTS FOR TREATMENT OF ALCOHOL USE DISORDER SERVICIO ANDALUZ DE SALUD (ES) 2022-05-12 US claimed
US-20260078161-A1 METHODS OF USING ACTIVIN RECEPTOR TYPE II VARIANTS KEROS THERAPEUTICS INC (US) 2026-03-19 US disclosed
EP-3452041-B1 COMPOSITIONS AND METHODS FOR ADMINISTERING PPAR-GAMMA-AGONISTS, SURFACTANT PEPTIDES AND PHOSPHOLIPIDS LOS ANGELES BIOMEDICAL RES INST HARBOR UCLA MEDICAL CT (US) 2026-01-14 EP disclosed
US-12337023-B2 Methods and compositions for the prevention and treatment of disease STEALTH BIOTHERAPEUTICS INC. (US) 2025-06-24 US disclosed
EP-4531879-A1 COMPOSITIONS OF SECRETORY AND/OR CATALYTIC CELLS AND METHODS USING THE SAME Flagship Pioneering Innovations VI, LLC (US) 2025-04-09 EP disclosed
CN-114729311-B Preparation method of brown adipocytes 株式会社片冈制作所 2025-02-18 CN disclosed
EP-3733203-A1 PROPHYLACTIC AGENT AND/OR THERAPEUTIC AGENT FOR CATARACT, MEDICINAL COMPOSITION FOR PREVENTING AND/OR TREATING CATARACT, USE OF PPAR ACTIVATOR FOR PRODUCING SAME, AND EYEDROPS University of Fukui (JP) 2020-11-04 EP disclosed
CN-111511402-A Agent for preventing and/or treating cataract, pharmaceutical composition for preventing and/or treating cataract, use of PPAR activator for producing the same, and eye drop 国立大学法人福井大学 2020-08-07 CN disclosed
WO-2019199979-A1 ANTIBACTERIAL COMPOUNDS THE GENERAL HOSPITAL CORPORATION (US) 2019-10-17 WO disclosed
WO-2019199979-A1 ANTIBACTERIAL COMPOUNDS THE GENERAL HOSPITAL CORPORATION (US) 2019-10-17 WO disclosed
US-20150004144-A1 DIFFERENTIATION INTO BROWN ADIPOCYTES THE GENERAL HOSPITAL CORPORATION (US) 2015-01-01 US disclosed
US-20040235019-A1 Solid phase synthesis; drug screening; diabetes; obesity AGOURON PHARMACEUTICALS, INC. 2004-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230043587-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DISEASE COL2A1, ALPI, COL14A1 MEN1 947/4885KMT2A 3677/4885CYP3A4 4287/4885
US-20260078161-A1 METHODS OF USING ACTIVIN RECEPTOR TYPE II VARIANTS ACVR2A, ACVRL1, ACVR2B MEN1 1515/4885KMT2A 2771/4885CYP3A4 3323/4885
US-12337023-B2 Methods and compositions for the prevention and treatment of disease COL2A1, ALPI, COL14A1 MEN1 947/4885KMT2A 3677/4885CYP3A4 4287/4885
US-20220324796-A1 ANTIBIOTIC COMPOUNDS NRDC, MMP8, CLPP MEN1 3319/4885KMT2A 3808/4885CYP3A4 2864/4885
US-20220142985-A1 AGENTS FOR TREATMENT OF ALCOHOL USE DISORDER ADH1A, ADH5, ADH1C MEN1 4875/4885KMT2A 1365/4885CYP3A4 1482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.