Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NHERF1 | O14745 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | STK33 | Q9BYT3 | 2/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.41 |
| ▸ | CCKAR | P32238 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711642 | 0.93 | NHERF1 (0.49) | NHERF1EGFRPIK3CAMGAMGAA | |
| SCHEMBL6713754 | 0.92 | SERPINE1 (0.43) | NHERF1GAASTK33PLCG2 | |
| SCHEMBL6710112 | 0.90 | MAP3K5 (0.45) | NHERF1NPC1LMNARAB9ASTK33 | |
| SCHEMBL6710125 | 0.89 | SERPINE1 (0.48) | NHERF1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL6711486 | 0.89 | NPC1 (0.42) | EGFRPIK3CANPC1LMNARAB9A | |
| SCHEMBL6710216 | 0.89 | KCNMA1 (0.46) | NHERF1GAANPC1LMNARAB9A | |
| SCHEMBL6708019 | 0.88 | GPR35 (0.44) | NHERF1GAASTK33PLCG2 | |
| SCHEMBL6711816 | 0.88 | PLCG2 (0.44) | NHERF1LMNASTK33PYGLPLCG2 | |
| SCHEMBL6710087 | 0.88 | PLCG2 (0.39) | NHERF1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL6709211 | 0.88 | PLCG2 (0.39) | NHERF1LMNASTK33PYGLPLCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | NHERF1 1641/4885EGFR 2231/4885PIK3CA 2906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.