Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.48 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 12/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711093 | 0.88 | KMT2A (0.43) | KMT2AMEN1ALDH1A1PKMPOLB | |
| SCHEMBL8372478 | 0.82 | PDIA6 (0.46) | KMT2AMEN1ALDH1A1PKMPOLB | |
| Potassium Ion SCHEMBL6710228 | 0.81 | GPR174 (0.48) | KMT2AMEN1ALDH1A1PKMPOLB | |
| SCHEMBL6712838 | 0.79 | POLB (0.41) | KMT2AMEN1ALDH1A1PKMPOLB | |
| SCHEMBL6712693 | 0.77 | GPR174 (0.48) | KMT2AMEN1ALDH1A1PKMPOLB | |
| SCHEMBL6714658 | 0.77 | GPR174 (0.48) | KMT2AMEN1ALDH1A1PKMPOLB | |
| SCHEMBL1129346 | 0.77 | GPR174 (0.48) | KMT2AMEN1ALDH1A1PKMPOLB | |
| SCHEMBL6710230 | 0.77 | GPR174 (0.48) | KMT2AMEN1ALDH1A1PKMPOLB | |
| SCHEMBL22140311 | 0.73 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1PKMPOLB | |
| SCHEMBL10338925 | 0.73 | GPR174 (0.58) | KMT2AMEN1ALDH1A1PKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6740722-B2 | Low density acrylic fiber | SOLUTIA INC. | 2004-05-25 | — | — | US | disclosed |
| US-20030057593-A1 | Low density acrylic fiber | ASCEND PERFORMANCE MATERIALS OPERATIONS LLC | 2003-03-27 | — | — | US | disclosed |