Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NHERF1 | O14745 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 4/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 3/20 | 0.44 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711906 | 0.93 | NHERF1 (0.46) | NHERF1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL6708921 | 0.92 | ALOX15 (0.51) | NHERF1MEN1KMT2ARXFP1PYGL | |
| SCHEMBL6709900 | 0.88 | NPC1 (0.47) | NPC1RAB9ALMNASMN1; SMN2GAA | |
| SCHEMBL6711816 | 0.86 | PLCG2 (0.44) | NHERF1LMNAMEN1KMT2ARXFP1 | |
| SCHEMBL6709221 | 0.85 | ALOX15 (0.46) | NHERF1PYGL | |
| SCHEMBL6707766 | 0.85 | NPC1 (0.45) | NPC1RAB9ALMNASMN1; SMN2GAA | |
| SCHEMBL6713754 | 0.84 | SERPINE1 (0.43) | NHERF1GAARXFP1STK33KDM4E | |
| SCHEMBL6712151 | 0.84 | FLT3 (0.48) | NPC1RAB9ALMNASMN1; SMN2GAA | |
| SCHEMBL6711722 | 0.84 | KDM4E (0.57) | NHERF1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL6710194 | 0.84 | NSD2 (0.50) | NHERF1NPC1RAB9ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | NHERF1 1641/4885NPC1 3891/4885RAB9A 3732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.