Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CCKAR | P32238 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711486 | 0.93 | NPC1 (0.42) | NPC1RAB9ALMNASMN1; SMN2HIF1A | |
| SCHEMBL6711642 | 0.88 | NHERF1 (0.49) | NPC1RAB9ALMNASMN1; SMN2RXFP1 | |
| SCHEMBL6709221 | 0.87 | ALOX15 (0.46) | GPR35 | |
| SCHEMBL6707766 | 0.85 | NPC1 (0.45) | NPC1RAB9ALMNASMN1; SMN2IDO1 | |
| SCHEMBL6711679 | 0.84 | GPR35 (0.50) | NPC1RAB9ANPSR1RXFP1KDM4E | |
| SCHEMBL6707911 | 0.84 | KDM4E (0.57) | NPC1RAB9ANPSR1RXFP1KDM4E | |
| SCHEMBL6711741 | 0.84 | HIF1A (0.47) | HIF1ANPSR1RXFP1GPR35 | |
| SCHEMBL6707909 | 0.84 | MAP3K5 (0.41) | LMNAHIF1ANPSR1RXFP1GPR35 | |
| SCHEMBL6709089 | 0.84 | RXFP1 (0.38) | HIF1ANPSR1RXFP1GPR35 | |
| SCHEMBL6713465 | 0.84 | GPR35 (0.43) | HIF1ANPSR1RXFP1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | NPC1 3891/4885RAB9A 3732/4885LMNA 4062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.