Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPD | P32754 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19539408 | 0.78 | P2RX7 (0.41) | P2RX7MEN1KMT2AHPDALDH1A1 | |
| SCHEMBL21076591 | 0.77 | POLB (0.37) | P2RX7MEN1KMT2AHPDALDH1A1 | |
| SCHEMBL19539409 | 0.76 | TLR7 (0.43) | P2RX7MEN1KMT2AHPDALDH1A1 | |
| SCHEMBL9680964 | 0.73 | MAPT (0.42) | MEN1KMT2AALDH1A1NPC1MAPT | |
| SCHEMBL25374364 | 0.69 | EGFR (0.41) | MEN1KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL30401360 | 0.69 | EGFR (0.41) | MEN1KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL18226430 | 0.68 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1NPC1MAPT | |
| SCHEMBL7851767 | 0.68 | BDKRB1 (0.45) | MEN1KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL253175 | 0.68 | L3MBTL1 (0.44) | ALDH1A1HTTNPC1MAPTMAPK1 | |
| SCHEMBL9682000 | 0.68 | MAPT (0.51) | MEN1KMT2AALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063761-A1 | 2-(biarylalkyl)amino-3-(fluoroalkanoylamino)pyridine derivatives | KUDUK SCOTT D (US) | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063761-A1 | 2-(biarylalkyl)amino-3-(fluoroalkanoylamino)pyridine derivatives | BDKRB1, BDKRB2, LTB4R2 | P2RX7 131/4885MEN1 3316/4885KMT2A 3694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.