Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 6/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1853850 | 0.79 | NAAA (0.43) | NAAASIRT3PTPN1EYA3L3MBTL1 | |
| SCHEMBL1860426 | 0.77 | HDAC3 (0.50) | NAAASIRT3PTPN1EYA3L3MBTL1 | |
| SCHEMBL1856867 | 0.77 | TMEM97 (0.50) | NAAASIRT3PTPN1EYA3L3MBTL1 | |
| SCHEMBL5040035 | 0.76 | TMEM97 (0.48) | NAAASIRT3PTPN1EYA3L3MBTL1 | |
| Acetic Acid SCHEMBL27738439 | 0.76 | TMEM97 (0.48) | NAAASIRT3PTPN1EYA3L3MBTL1 | |
| SCHEMBL1852984 | 0.72 | MLYCD (0.51) | NAAAL3MBTL1CA2SMN1; SMN2FOLH1 | |
| SCHEMBL31314643 | 0.72 | EYA3 (0.72) | SIRT3PTPN1EYA3 | |
| SCHEMBL4331561 | 0.71 | TMEM97 (0.45) | NAAASIRT3PTPN1EYA3L3MBTL1 | |
| SCHEMBL6022117 | 0.70 | PTPN1 (0.51) | SIRT3PTPN1EYA3HDAC3 | |
| SCHEMBL1862629 | 0.70 | NAAA (0.55) | NAAAL3MBTL1CA2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | claimed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | claimed |