Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 known ✓ | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 known ✓ | P47870 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982888 | 0.96 | CTSB (0.50) | CTSBHSD11B1P2RY4P2RY2LOXL2 | |
| SCHEMBL1058401 | 0.96 | CTSB (0.50) | CTSBHSD11B1P2RY4P2RY2LOXL2 | |
| SCHEMBL10441196 | 0.96 | CTSB (0.50) | CTSBHSD11B1P2RY4P2RY2LOXL2 | |
| SCHEMBL982889 | 0.96 | CTSB (0.50) | CTSBHSD11B1P2RY4P2RY2LOXL2 | |
| Potassium Ion SCHEMBL23749118 | 0.86 | CTSB (0.39) | CTSBHSD11B1P2RY4P2RY2PSIP1 | |
| Ammonia Solution, Strong SCHEMBL11072985 | 0.85 | CTSB (0.42) | CTSBHSD11B1P2RY4P2RY2LOXL2 | |
| Potassium Ion SCHEMBL3216153 | 0.83 | LIPG (0.43) | CTSBTSHRCYP3A4CYP2D6 | |
| SCHEMBL5267610 | 0.82 | P2RY4 (0.39) | CTSBHSD11B1P2RY4P2RY2LMNA | |
| Potassium Ion SCHEMBL23749105 | 0.82 | GABRA1 (0.39) | CTSBHSD11B1P2RY4P2RY2LOXL2 | |
| Potassium Ion SCHEMBL23749114 | 0.81 | LIPG (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751349-A | Method for continuously synthesizing 8-methylquinoline | 江苏优士化学有限公司 | 2025-04-04 | — | — | CN | claimed |
| US-6670315-B1 | Low pollution solvents and emulsions especially useful in cleaning soils from painted and unpainted metal and plastic surfaces | HENKEL CORPORATION | 2003-12-30 | — | — | US | claimed |
| US-6423677-B1 | SPARINGLY WATER SOLUBLE ORGANIC SOLVENT; SOLUBIZING SURFACTANT; FORMING A BARELY CLEAR, TOTALLY WATER SOLUBLE SOLUTION WHEN DILUTED WITH WATER | BUCKEYE INTERNATIONAL, INC. | 2002-07-23 | — | — | US | claimed |
| US-20020058600-A1 | Cleaner/degreaser concentrate compositions | VAN EENAM DONALD N (US) | 2002-05-16 | — | — | US | claimed |
| EP-0525032-B1 | IMPROVED AQUEOUS DEGREASER COMPOSITIONS | BUCKEYE INT (US) | 2000-01-19 | — | — | EP | claimed |
| US-5849682-A | Cleaner/degreaser concentrate compositions | VAN EENAM DONALD N (US) | 1998-12-15 | — | — | US | claimed |
| EP-0479888-B1 | IMPROVED BUILDER-CONTAINING AQUEOUS CLEANER/DEGREASER MICROEMULSION COMPOSITIONS | BUCKEYE INT (US) | 1996-12-18 | — | — | EP | claimed |
| US-5585341-A | NONAQUEOUS, WATER SOLUBLE | BUCKEYE INTERNATIONAL, INC. (US) | 1996-12-17 | — | — | US | claimed |
| EP-0479908-B1 | IMPROVED AQUEOUS CLEANER/DEGREASER COMPOSITIONS | BUCKEYE INT (US) | 1995-03-08 | — | — | EP | claimed |
| EP-0506744-A4 | AQUEOUS CLEANER/DEGREASER EMULSION COMPOSITIONS | — | 1993-09-22 | — | — | EP | claimed |
| EP-0479908-A4 | IMPROVED AQUEOUS CLEANER/DEGREASER COMPOSITIONS | — | 1992-06-17 | — | — | EP | claimed |
| EP-0479888-A4 | IMPROVED BUILDER-CONTAINING AQUEOUS CLEANER/DEGREASER MICROEMULSION COMPOSITIONS | — | 1992-06-03 | — | — | EP | claimed |
| EP-0479888-A1 | IMPROVED BUILDER-CONTAINING AQUEOUS CLEANER/DEGREASER MICROEMULSION COMPOSITIONS. | BUCKEYE INT (US) | 1992-04-15 | — | — | EP | claimed |
| EP-0479908-A1 | IMPROVED AQUEOUS CLEANER/DEGREASER COMPOSITIONS. | BUCKEYE INT (US) | 1992-04-15 | — | — | EP | claimed |
| US-5080822-A | AQUEOUS DEGREASER COMPOSITIONS CONTAINING AN ORGANIC SOLVENT AND A SOLUBILIZING COUPLER | BUCKEYE INTERNATIONAL, INC. (US) | 1992-01-14 | — | — | US | claimed |
| US-5080831-A | Water soluble solvent, surfactant and coupler, stability | BUCKEYE INTERNATIONAL, INC. (US) | 1992-01-14 | — | — | US | claimed |
| WO-1991015565-A1 | IMPROVED AQUEOUS DEGREASER COMPOSITIONS | BUCKEYE INTERNATIONAL, INC. (US) | 1991-10-17 | — | — | WO | claimed |
| WO-1991009104-A1 | AQUEOUS CLEANER/DEGREASER EMULSION COMPOSITIONS | BUCKEYE INTERNATIONAL, INC. (US) | 1991-06-27 | — | — | WO | claimed |
| WO-1991000337-A1 | IMPROVED BUILDER-CONTAINING AQUEOUS CLEANER/DEGREASER MICROEMULSION COMPOSITIONS | BUCKEYE INTERNATIONAL, INC. (US) | 1991-01-10 | — | — | WO | claimed |
| WO-1991000336-A1 | IMPROVED AQUEOUS CLEANER/DEGREASER COMPOSITIONS | BUCKEYE INTERNATIONAL, INC. (US) | 1991-01-10 | — | — | WO | claimed |