Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYLK | Q15746 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6238430 | 0.81 | MAPT (0.47) | MAPTKMT2ATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL24054541 | 0.79 | MAPT (0.44) | MAPTKMT2ASMN1; SMN2ALDH1A1KMO | |
| SCHEMBL30198077 | 0.79 | MAPT (0.44) | MAPTKMT2ASMN1; SMN2ALDH1A1KMO | |
| SCHEMBL6887258 | 0.78 | ALDH1A1 (0.48) | MYLKKMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1429199 | 0.75 | MYLK (0.48) | MYLKKMT2AALDH1A1MAOAMAOB | |
| SCHEMBL29811358 | 0.75 | MAPT (0.53) | MAPTKMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1319021 | 0.75 | MAPT (0.53) | MAPTKMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8401734 | 0.74 | MYLK (0.48) | MYLKKMT2AALDH1A1MAOAMAOB | |
| SCHEMBL3932038 | 0.72 | KDM4E (0.56) | MAPTKMT2ATP53NPSR1KDM4E | |
| SCHEMBL9046095 | 0.72 | PLA2G2A (0.46) | MAPTKMT2ATP53SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147739-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147739-A1 | Novel anti-infectives | RPL5, RPL7, RPL35 | MYLK 2820/4885MAPT 4204/4885KMT2A 4733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.