Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239419 | 0.86 | ALDH1A1 (0.48) | ALDH1A1NPSR1TSHRUSP2HPGD | |
| SCHEMBL1061987 | 0.81 | PGR (0.60) | ALDH1A1NPSR1KDM4EHPGDLMNA | |
| SCHEMBL17208786 | 0.81 | ALDH1A1 (0.51) | ALDH1A1NPSR1TSHRUSP2HPGD | |
| SCHEMBL11688278 | 0.81 | ALDH1A1 (0.51) | ALDH1A1NPSR1TSHRUSP2HPGD | |
| SCHEMBL11389425 | 0.81 | ALDH1A1 (0.51) | ALDH1A1NPSR1TSHRUSP2HPGD | |
| SCHEMBL1150044 | 0.80 | KDM4E (0.56) | PIM1PIM3KDM4EMEN1LMNA | |
| SCHEMBL20968383 | 0.79 | ALDH1A1 (0.54) | ALDH1A1NPSR1TSHRUSP2HPGD | |
| SCHEMBL2453991 | 0.79 | PGR (0.55) | ALDH1A1NPSR1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL6236243 | 0.78 | ALDH1A1 (0.57) | ALDH1A1NPSR1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL6738655 | 0.78 | MYLK (0.52) | ALDH1A1NPSR1KDM4EHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040034041-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2004-02-19 | — | — | US | disclosed |
| EP-1292310-A1 | NOVEL ANTI-INFECTIVES | SmithKline Beecham Corporation (US) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001085172-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034041-A1 | Novel anti-infectives | CTSL, MMP8, SERPINB1 | ALDH1A1 4350/4885NPSR1 3785/4885PIM1 2715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.