Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4474152 | 0.77 | RAB9A (0.55) | RAB9ANPC1STAT3KCNMA1SMN1; SMN2 | |
| SCHEMBL4333687 | 0.76 | CTSD (0.67) | RAB9ANPC1PLAUKCNMA1SMN1; SMN2 | |
| SCHEMBL6704959 | 0.76 | TAS1R3 (0.46) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL13294935 | 0.75 | HDAC7 (0.53) | RAB9ANPC1STAT3KCNMA1SMN1; SMN2 | |
| SCHEMBL1003770 | 0.75 | PLK1 (0.54) | RAB9ANPC1KCNMA1SMN1; SMN2MAPT | |
| SCHEMBL8115080 | 0.74 | RAB9A (0.46) | RAB9ANPC1PLAUKCNMA1SMN1; SMN2 | |
| SCHEMBL14038245 | 0.74 | ACHE (0.57) | PLAUALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL704024 | 0.74 | ACHE (0.57) | PLAUALDH1A1HPGDMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8111821 | 0.73 | RAB9A (0.45) | RAB9ANPC1PLAUKCNMA1SMN1; SMN2 | |
| SCHEMBL136101 | 0.71 | MAPT (0.60) | RAB9ANPC1PLAUSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043995-A1 | Novel triazole derivatives, process for their preparation and pharmaceutical compositions containing them | BIGNON ERIC (FR) | 2004-03-04 | — | — | US | disclosed |
| EP-0984960-B1 | N-TRIAZOLYL-2-INDOLECARBOXAMIDES AND THEIR USE AS CCK-A AGONISTS | SANOFI SYNTHELABO (FR) | 2003-02-05 | — | — | EP | disclosed |
| EP-0984960-A1 | N-TRIAZOLYL-2-INDOLECARBOXAMIDES AND THEIR USE AS CCK-A AGONISTS | SANOFI-SYNTHELABO (FR) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998051686-A1 | N-TRIAZOLYL-2-INDOLECARBOXAMIDES AND THEIR USE AS CCK-A AGONISTS | SANOFI-SYNTHELABO (FR) | 1998-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043995-A1 | Novel triazole derivatives, process for their preparation and pharmaceutical compositions containing them | CCKAR, CCKBR, NPY1R | RAB9A 1127/4885NPC1 1845/4885PLAU 2897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.