Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749879 | 0.87 | CASP1 (0.40) | PTGS2CASP1CCR2PTGS1 | |
| SCHEMBL6746349 | 0.86 | PTGS2 (0.41) | PTGS2CASP1SCDPTGS1 | |
| SCHEMBL6745114 | 0.85 | SDHB (0.38) | PTGS2CASP1PTGS1 | |
| SCHEMBL6746439 | 0.85 | CASP1 (0.39) | PTGS2CASP1CCR2PTGS1HTT | |
| SCHEMBL6745120 | 0.84 | ACLY (0.35) | PTGS2CASP1KMT2ARAB9APTGS1 | |
| SCHEMBL6750004 | 0.84 | PTGS2 (0.46) | PTGS2CASP1PTGS1 | |
| SCHEMBL6746293 | 0.84 | PTGS2 (0.38) | PTGS2CASP1KMT2ARAB9AMEN1 | |
| SCHEMBL6745050 | 0.82 | PTGS2 (0.42) | PTGS2CASP1PTGS1 | |
| SCHEMBL6749791 | 0.82 | PTGS2 (0.40) | PTGS2PGRMAPT | |
| SCHEMBL6747309 | 0.81 | PTGS2 (0.47) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | disclosed |