Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095610 | 0.80 | RAB9A (0.47) | HPGDALDH1A1HTTMEN1KMT2A | |
| SCHEMBL7092287 | 0.78 | RAB9A (0.44) | HPGDALDH1A1GAAHTTMEN1 | |
| SCHEMBL7097980 | 0.75 | GRM5 (0.41) | HPGDALDH1A1GAAHTTMEN1 | |
| SCHEMBL6737820 | 0.71 | RAB9A (0.45) | HDAC1HDAC2HDAC3HPGDALDH1A1 | |
| SCHEMBL6484868 | 0.71 | ALDH1A1 (0.35) | HDAC1HDAC2HDAC3ALDH1A1GAA | |
| SCHEMBL6698677 | 0.71 | ALDH1A1 (0.35) | HPGDALDH1A1GAAHTTMEN1 | |
| SCHEMBL7990575 | 0.70 | HDAC3 (0.41) | HDAC1HDAC2HDAC3HPGDALDH1A1 | |
| SCHEMBL7088459 | 0.70 | ALOX5 (0.41) | ALDH1A1KMT2AKDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL4266412 | 0.69 | KCNK3 (0.61) | HPGDALDH1A1ALOX12GAAHTT | |
| SCHEMBL7476442 | 0.67 | ALDH1A1 (0.37) | HDAC1HPGDALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686484-B2 | ANTICOAGULANTS; SERINE PROTEASE INHIBITOR | PHARMACIA CORPORATION | 2004-02-03 | — | — | US | claimed |