Carbendazim — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRB1 ADRB2 ADRB3 CYP11B1 DPP4 FGFR1 FGFR2 FGFR3 FGFR4 HRH1 JAK1 JAK2 JAK3 KCNA1 KCNA10 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNB1 KCNB2 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNG2 KCNG3 KCNG4 KCNH1 KCNH2 KCNH3 KCNH4 KCNH5 KCNH6 KCNH7 KCNH8 KCNQ1 KCNQ2 KCNQ3 KCNQ4 KCNQ5 KCNS1 KCNS2 KCNS3 KCNV1 KCNV2 KDR KIT NA OPRD1 OPRK1 OPRM1 P PDGFRB PIK3CD SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SMO TYK2 pol rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Carbendazim. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	KDR known ✓	P35968	1/20	0.60

▸	OPRK1 known ✓	P41145	1/20	0.59

▸	LMNA	P02545	4/20	0.64

▸	RAB9A	P51151	11/20	0.62

▸	NPC1	O15118	10/20	0.62

▸	PKM	P14618	5/20	0.62

▸	MEN1	O00255	5/20	0.62

▸	KMT2A	Q03164	5/20	0.62

▸	HSP90AA1	P07900	1/20	0.62

▸	PAX8	Q06710	1/20	0.62

▸	SMN1; SMN2	Q16637	5/20	0.61

▸	ADORA2A	P29274	2/20	0.61

▸	MAOB	P27338	1/20	0.61

▸	MAPT	P10636	2/20	0.61

▸	CYP3A4	P08684	2/20	0.60

▸	ALDH1A1	P00352	3/20	0.60

▸	USP2	O75604	2/20	0.60

▸	CYP1A2	P05177	2/20	0.60

▸	ABCC4	O15439	1/20	0.60

▸	ABL1	P00519	1/20	0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Carbendazim SCHEMBL29352313	1.00	LMNA (0.64)	LMNARAB9ANPC1PKMMEN1
Carbendazim SCHEMBL8427009	0.94	LMNA (0.71)	LMNARAB9ANPC1PKMMEN1
Carbendazim SCHEMBL29357746	0.94	LMNA (0.71)	LMNARAB9ANPC1PKMMEN1
Carbendazim SCHEMBL21051	0.94	LMNA (0.71)	LMNARAB9ANPC1PKMMEN1
Carbendazim SCHEMBL11360169	0.93	LMNA (0.69)	LMNARAB9ANPC1PKMMEN1
Carbendazim SCHEMBL74664	0.93	LMNA (0.69)	LMNARAB9ANPC1PKMMEN1
Carbendazim SCHEMBL5449176	0.93	LMNA (0.69)	LMNARAB9ANPC1PKMMEN1
Carbendazim SCHEMBL8716640	0.93	LMNA (0.69)	LMNARAB9ANPC1PKMMEN1
Carbendazim SCHEMBL6542037	0.91	LMNA (0.68)	LMNARAB9ANPC1PKMMEN1
Carbendazim SCHEMBL5440632	0.89	LMNA (0.64)	LMNARAB9ANPC1PKMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-1385068-A	Composition with insecticidal, acaricidal and bactericidal activities	JIANGSU PESTICIDE INST (CN)	2002-12-18	—	—	CN	claimed
US-12325646-B2	Fertigation water treatment	UNIVERSITY OF GUELPH (CA)	2025-06-10	—	—	US	disclosed
US-20250024837-A1	PESTICIDE SYSTEM	BANISH, MICHELE	2025-01-23	—	—	US	disclosed
US-20220234916-A1	WATER TREATMENT	UNIVERSITY OF GUELPH (CA)	2022-07-28	—	—	US	disclosed
US-20110274677-A1	Biological Pest Control Mixture Containing D-Limonene and Nutmeg Oil	MULLEN BOB	2011-11-10	—	—	US	disclosed
WO-2009135289-A1	BIOLOGICAL PEST CONTROL MIXTURE CONTAINING D-LIMONENE AND NUTMEG OIL	MULLEN BOB (CA)	2009-11-12	—	—	WO	disclosed
US-20070043070-A1	Weak base salts	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA	2007-02-22	—	—	US	disclosed
US-20060276339-A1	Methods and compositions for increasing the efficacy of biologically-active ingredients	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM	2006-12-07	—	—	US	disclosed
EP-1606290-A1	WEAK BASE SALTS	Arizona Board of Regents, acting on behalf of the University of Arizona (US)	2005-12-21	—	—	EP	disclosed
CN-1535580-A	Pesticide compound with insecticidal, acaricidal and fungicidal activity	江苏省农药研究所	2004-10-13	—	—	CN	disclosed
WO-2004081006-A1	WEAK BASE SALTS	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US)	2004-09-23	—	—	WO	disclosed
CN-1385068-A	Composition with insecticidal, acaricidal and bactericidal activities	JIANGSU PESTICIDE INST (CN)	2002-12-18	—	—	CN	disclosed
US-4103456-A	Device and method for treating trees	HENDRIXSON DALE Z	1978-08-01	—	—	US	disclosed
US-3992813-A	Tree treating system	FRESHEL DAVID C	1976-11-23	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20070043070-A1	Weak base salts	H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, SLC9A1, SLC10A1	KDR 4697/4885OPRK1 288/4885LMNA 2435/4885
US-20060276339-A1	Methods and compositions for increasing the efficacy of biologically-active ingredients	ENPP1, ENPP3, SMPD1	KDR 4128/4885OPRK1 4875/4885LMNA 3199/4885
US-20250024837-A1	PESTICIDE SYSTEM	ACHE, PFAS, FPGS	KDR 3461/4885OPRK1 4394/4885LMNA 3099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.