Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Carbendazim. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 known ✓ | P00519 | 1/20 | 0.64 |
| ▸ | KDR known ✓ | P35968 | 1/20 | 0.64 |
| ▸ | HSP90AA1 known ✓ | P07900 | 1/20 | 0.63 |
| ▸ | MAPK14 known ✓ | Q16539 | 1/20 | 0.62 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.61 |
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 9/20 | 0.63 |
| ▸ | NPC1 | O15118 | 8/20 | 0.63 |
| ▸ | PKM | P14618 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbendazim SCHEMBL5449176 | 1.00 | LMNA (0.69) | LMNACYP3A4CYP1A2ALDH1A1USP2 | |
| Carbendazim SCHEMBL8716640 | 1.00 | LMNA (0.69) | LMNACYP3A4CYP1A2ALDH1A1USP2 | |
| Carbendazim SCHEMBL29357746 | 0.98 | LMNA (0.71) | LMNACYP3A4CYP1A2ALDH1A1USP2 | |
| Carbendazim SCHEMBL8427009 | 0.98 | LMNA (0.71) | LMNACYP3A4CYP1A2ALDH1A1USP2 | |
| Carbendazim SCHEMBL21051 | 0.98 | LMNA (0.71) | LMNACYP3A4CYP1A2ALDH1A1USP2 | |
| Carbendazim SCHEMBL11360169 | 0.97 | LMNA (0.69) | LMNACYP3A4CYP1A2ALDH1A1USP2 | |
| Carbendazim SCHEMBL6542037 | 0.95 | LMNA (0.68) | LMNACYP3A4CYP1A2ALDH1A1USP2 | |
| Carbendazim SCHEMBL675275 | 0.93 | LMNA (0.64) | LMNACYP3A4CYP1A2ALDH1A1USP2 | |
| Carbendazim SCHEMBL5440632 | 0.93 | LMNA (0.64) | LMNACYP3A4CYP1A2ALDH1A1USP2 | |
| Carbendazim SCHEMBL5443295 | 0.93 | LMNA (0.64) | LMNACYP3A4CYP1A2ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118975562-A | Fungicidal compositions | 先正达农作物保护股份公司 | 2024-11-19 | — | — | CN | claimed |
| CN-118354672-A | Fungicidal compositions | 先正达农作物保护股份公司 | 2024-07-16 | — | — | CN | claimed |
| US-11974572-B2 | Fungicidal compositions | SYGENTA PARTICIPATIONS AG (CH) | 2024-05-07 | — | — | US | claimed |
| CN-117126917-A | Method for rapidly identifying resistance of black seed pumpkin resources to wilt | 云南农业大学 | 2023-11-28 | — | — | CN | claimed |
| US-20230276805-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2023-09-07 | — | — | US | claimed |
| US-20230270114-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-31 | — | — | US | claimed |
| WO-2023099460-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-08 | — | — | WO | claimed |
| US-20230125322-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | US | claimed |
| US-20230131427-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | US | claimed |
| EP-4161273-A1 | FUNGICIDAL COMPOSITIONS | Syngenta Crop Protection AG (CH) | 2023-04-12 | — | — | EP | claimed |
| EP-3174397-A1 | FUNGICIDAL COMPOSITIONS | Syngenta Participations AG (CH) | 2017-06-07 | — | — | EP | claimed |
| WO-2017063973-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-04-20 | — | — | WO | claimed |
| CN-106535636-A | Fungicidal compositions | 先正达参股股份有限公司 | 2017-03-22 | — | — | CN | claimed |
| CN-105732512-A | Carbendazim production technology | 江苏泰仓农化有限公司 | 2016-07-06 | — | — | CN | claimed |
| WO-2016015979-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-04 | — | — | WO | claimed |
| EP-2331535-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-07-22 | — | — | EP | claimed |
| EP-2238132-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-08-01 | — | — | EP | claimed |
| CN-1183894-A | Sanduo mixture and its recompounding process | LI ANJIANG (CN) | 1998-06-10 | — | — | CN | claimed |
| CN-1120889-A | Agricultural chemical Genfukang for preventing and curing root rot | WANG MANPING (CN) | 1996-04-24 | — | — | CN | claimed |
| CN-1059826-A | A kind of multipurpose composite fungus killing agent | JIANGSU PROV ACAD AGRI SCI (CN) | 1992-04-01 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230270114-A1 | FUNGICIDAL COMPOSITIONS | CYP51A1, CYP4X1, CYP1B1 | ABL1 1254/4885KDR 4701/4885HSP90AA1 1697/4885 |
| US-20230125322-A1 | FUNGICIDAL COMPOSITIONS | CYP51A1, CYP4X1, CYP1B1 | ABL1 1254/4885KDR 4701/4885HSP90AA1 1697/4885 |
| US-20230131427-A1 | FUNGICIDAL COMPOSITIONS | CYP51A1, CYP4X1, CYP1B1 | ABL1 1254/4885KDR 4701/4885HSP90AA1 1697/4885 |
| US-20230276805-A1 | FUNGICIDAL COMPOSITIONS | CYP51A1, CYP4X1, CYP1B1 | ABL1 1254/4885KDR 4701/4885HSP90AA1 1697/4885 |
| US-11974572-B2 | Fungicidal compositions | CYP51A1, CYP4X1, CYP1B1 | ABL1 1254/4885KDR 4701/4885HSP90AA1 1697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.