Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.51 |
| ▸ | AHR | P35869 | 3/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | PCSK9 | Q8NBP7 | 6/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10544271 | 0.80 | NLRP3 (0.43) | LOXL2 | |
| SCHEMBL28338445 | 0.77 | LOXL2 (0.69) | AHRLOXL2PCSK9 | |
| SCHEMBL401081 | 0.77 | LOXL2 (0.69) | AHRLOXL2PCSK9 | |
| SCHEMBL29403791 | 0.77 | LOXL2 (0.69) | AHRLOXL2PCSK9 | |
| SCHEMBL28335219 | 0.75 | LOXL2 (0.67) | AHRLOXL2PCSK9 | |
| SCHEMBL7738327 | 0.75 | AKR1B1 (0.38) | TAAR1AHRADRA2AADRA2BADRA2C | |
| SCHEMBL11225248 | 0.74 | IDO1 (0.55) | AHRLOXL2PCSK9GUSB | |
| SCHEMBL25788675 | 0.74 | LOXL2 (0.47) | AHRLOXL2PCSK9GUSB | |
| SCHEMBL17508513 | 0.73 | AHR (0.55) | AHRLOXL2PCSK9 | |
| SCHEMBL9741433 | 0.73 | LOXL2 (0.43) | AHRLOXL2PCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067998-A1 | Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition | YANG JI CHEMICAL COMPANY LTD (KR) | 2004-04-08 | — | — | US | disclosed |
| EP-1322638-A1 | ANTIFUNGAL AND/OR ANTIPARASITIC PHARMACEUTICAL COMPOSITION AND NOVEL INDOLE DERIVATIVES AS ACTIVE PRINCIPLE OF SUCH A COMPOSITION | Yang Ji Chemical Company Ltd. (KR) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024685-A1 | INDOLE DERIVATIVES AND THEIR USE AS ANTIFUNGAL AND/OR ANTIPARASITIC AGENTS | YANG JI CHEMICAL COMPANY LTD. (KR) | 2002-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067998-A1 | Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition | IDO1, IDO2, TPH1 | TAAR1 2048/4885AHR 50/4885ADRA2A 1414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.