Fluoride Ion

Fluoride Ion

SCHEMBL6761841

[F-].[Na+].[Na+].[OH-]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Fluoride Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride Ion SCHEMBL28849892 0.87
Fluoride Ion SCHEMBL28267836 0.87
Water SCHEMBL430526 0.82
Water SCHEMBL9003163 0.82 CA1 (0.33)
Water SCHEMBL1313632 0.82 CA1 (0.33)
Water SCHEMBL3835534 0.82
Fluoride Ion SCHEMBL3823213 0.82
Water SCHEMBL8984178 0.82 CA1 (0.33)
Fluoride Ion SCHEMBL1782157 0.82
Water SCHEMBL9156696 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0436979-A1 Oral compositions UNILEVER N.V. (NL) 1991-07-17 EP claimed
CN-109341408-B Plate heat exchanger Integral cleaning method 孙永庆 2019-05-31 CN disclosed
CN-109341408-A Plate heat exchanger Integral cleaning method 孙永庆 2019-02-15 CN disclosed
CN-106435545-A Aluminum tube online anticorrosion reagent 合肥太通制冷科技有限公司 2017-02-22 CN disclosed
US-20040231563-A1 Aqueous film forming inorganic composition, inorganic foam, thermally insulating composite and for production thereof HIROSHI KOKUTA (JP) 2004-11-25 US disclosed
EP-0516765-B1 METHODS OF FORMING ELECTRONIC PACKAGES LANXIDE TECHNOLOGY CO LTD (US) 1997-07-09 EP disclosed
US-5526867-A Methods of forming electronic packages LANXIDE TECHNOLOGY COMPANY, LP (US) 1996-06-18 US disclosed
EP-0516765-A1 METHODS OF FORMING ELECTRONIC PACKAGES. LANXIDE TECHNOLOGY CO LTD (US) 1992-12-09 EP disclosed
US-5163499-A Method of forming electronic packages LANXIDE TECHNOLOGY COMPANY, LP (US) 1992-11-17 US disclosed