Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446851 | 0.82 | HCAR2 (0.36) | ALDH1A1LMNAHSD17B10HTTCA1 | |
| SCHEMBL1164307 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL14715925 | 0.78 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL20473345 | 0.78 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL4093235 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| Ethyl Acetate SCHEMBL8585320 | 0.77 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL789449 | 0.77 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL3868205 | 0.76 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL8074526 | 0.76 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL765474 | 0.76 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10ALOX15MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5058954-A | — | — | None | — | — | JP | disclosed |
| CN-107250097-B | Practical method for producing fluorine-containing α -ketocarboxylic acid esters | 中央硝子株式会社 | 2020-08-07 | — | — | CN | disclosed |
| US-20180050976-A1 | Practical Processes for Producing Fluorinated alpha-Ketocarboxylic Esters and Analogues Thereof | CENTRAL GLASS COMPANY, LIMITED (JP) | 2018-02-22 | — | — | US | disclosed |
| US-9828379-B2 | Pyrrolo-pyrrole carbamate and related organic compounds, pharmaceutical compositions, and medical uses thereof | ABIDE THERAPEUTICS, INC. (US) | 2017-11-28 | — | — | US | disclosed |
| US-9828379-B2 | Pyrrolo-pyrrole carbamate and related organic compounds, pharmaceutical compositions, and medical uses thereof | ABIDE THERAPEUTICS, INC. (US) | 2017-11-28 | — | — | US | disclosed |
| US-9828379-B2 | Pyrrolo-pyrrole carbamate and related organic compounds, pharmaceutical compositions, and medical uses thereof | ABIDE THERAPEUTICS, INC. (US) | 2017-11-28 | — | — | US | disclosed |
| CN-107250097-A | Practical method for producing fluorine-containing alpha-ketocarboxylic acid esters | 中央硝子株式会社 | 2017-10-13 | — | — | CN | disclosed |
| EP-2098501-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE FLUORINE-CONTAINING CARBONYL-ENE PRODUCT | CENTRAL GLASS CO LTD (JP) | 2017-08-23 | — | — | EP | disclosed |
| US-20160138059-A1 | Method for Manufacturing Optically Active Fluorolactic Acid Derivative | CENTRAL GLASS COMPANY, LIMITED (JP) | 2016-05-19 | — | — | US | disclosed |
| US-20160137649-A1 | PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ABIDE THERAPEUTICS, INC. | 2016-05-19 | — | — | US | disclosed |
| US-20160137649-A1 | PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ABIDE THERAPEUTICS, INC. | 2016-05-19 | — | — | US | disclosed |
| US-20160137649-A1 | PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ABIDE THERAPEUTICS, INC. | 2016-05-19 | — | — | US | disclosed |
| EP-3020818-A1 | METHOD FOR MANUFACTURING OPTICALLY ACTIVE FLUOROLACTIC ACID DERIVATIVE | Central Glass Company, Limited (JP) | 2016-05-18 | — | — | EP | disclosed |
| EP-3016653-A1 | PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | Abide Therapeutics, Inc. (US) | 2016-05-11 | — | — | EP | disclosed |
| CN-105378094-A | Method for manufacturing optically active fluorolactic acid derivative | CENTRAL GLASS CO LTD | 2016-03-02 | — | — | CN | disclosed |
| WO-2015003002-A1 | PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ABIDE THERAPEUTICS, INC. (US) | 2015-01-08 | — | — | WO | disclosed |
| WO-2015003002-A1 | PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ABIDE THERAPEUTICS, INC. (US) | 2015-01-08 | — | — | WO | disclosed |
| US-6815559-B2 | IMPORTANT INTERMEDIATES FOR MEDICINES AND LIQUID CRYSTALS. | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |
| US-20040049076-A1 | Process for producing 3,3,3-trifluoro-2-hydroxypropionic acid or its derivative | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-03-11 | — | — | US | disclosed |
| JP-H0558954-A | PRODUCTION OF TRIFLUOROLACTIC ACID DERIVATIVE | NIKKO KYODO CO LTD | 1993-03-09 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049076-A1 | Process for producing 3,3,3-trifluoro-2-hydroxypropionic acid or its derivative | ADH1C, HAAO, ADH1A | ALDH1A1 96/4885LMNA 3303/4885HSD17B10 30/4885 |
| US-20180050976-A1 | Practical Processes for Producing Fluorinated alpha-Ketocarboxylic Esters and Analogues Thereof | KHK, GCK, HK1 | ALDH1A1 1437/4885LMNA 2778/4885HSD17B10 978/4885 |
| US-20160137649-A1 | PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | FAAH, FAAH2, ABHD6 | ALDH1A1 2203/4885LMNA 4637/4885HSD17B10 1905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.