Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18883696 | 0.90 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19HTR2BTLR8 | |
| SCHEMBL942882 | 0.86 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19HTR2CHTR2B | |
| SCHEMBL11847000 | 0.83 | ALDH1A1 (0.52) | CYP1A2CYP2C19MEN1KMT2ANPC1 | |
| SCHEMBL24495023 | 0.83 | NCF1 (0.44) | CYP1A2CYP2C19KMT2AHTR7MAPT | |
| SCHEMBL4314586 | 0.82 | ALDH1A1 (0.45) | MEN1KMT2ARAB9AHTR7SLC6A2 | |
| SCHEMBL22400198 | 0.82 | HSD17B10 (0.43) | KMT2ARAB9AHTR7SLC6A2SLC6A4 | |
| SCHEMBL10458625 | 0.82 | KDM4E (0.41) | RAB9AHTR7SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7414992 | 0.82 | KDM4E (0.61) | CYP1A2CYP2C9CYP2C19RAB9AHTR7 | |
| SCHEMBL8876249 | 0.82 | SMN1; SMN2 (0.42) | HTR7SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL9323952 | 0.81 | PTGS2 (0.41) | CYP1A2CYP2C9CYP2C19KMT2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11175583-B2 | Silicon-containing resist underlayer film-forming composition having phenyl group-containing chromophore | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2021-11-16 | — | — | US | disclosed |
| US-10981894-B2 | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2021-04-20 | — | — | US | disclosed |
| US-10766877-B2 | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2020-09-08 | — | — | US | disclosed |
| US-10197917-B2 | Silicon-containing resists underlayer film-forming composition having phenyl group-containing chromophore | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2019-02-05 | — | — | US | disclosed |
| US-20170146906-A1 | SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION HAVING PHENYL GROUP-CONTAINING CHROMOPHORE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-05-25 | — | — | US | disclosed |
| US-6723745-B2 | PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL | SANKYO COMPANY, LIMITED (JP) | 2004-04-20 | — | — | US | disclosed |
| US-20030236297-A1 | Amino alcohol derivatives | SANKYO COMPANY, LIMITED (JP) | 2003-12-25 | — | — | US | disclosed |
| US-3932498-A | ANTIINFLAMMATORY, ANTIPYRETICS, ANALGESICS | MERCK & CO., INC. (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236297-A1 | Amino alcohol derivatives | CD4, ADH1C, ADH1A | CYP1A2 450/4885CYP2C9 1298/4885CYP2C19 1228/4885 |
| US-10766877-B2 | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | MC3R, MC1R, MC2R | CYP1A2 1383/4885CYP2C9 2713/4885CYP2C19 1504/4885 |
| US-10981894-B2 | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | MC3R, MC1R, MC2R | CYP1A2 1383/4885CYP2C9 2713/4885CYP2C19 1504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.