Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768483 | 0.86 | DRD3 (0.44) | ALDH1A1POLBHDAC3HDAC1DRD2 | |
| SCHEMBL6772103 | 0.85 | MCHR1 (0.51) | ALDH1A1NAMPTDRD2DRD3 | |
| SCHEMBL6769799 | 0.84 | MCHR1 (0.50) | NAMPTHDAC3DRD3GPR139 | |
| SCHEMBL6773548 | 0.84 | HDAC3 (0.49) | HDAC3HDAC1DRD2ADRA1ADRD3 | |
| SCHEMBL6774052 | 0.83 | POLB (0.43) | POLBNAMPTHDAC3HDAC1DRD2 | |
| SCHEMBL6773386 | 0.82 | TP53BP1 (0.49) | TP53BP1ALDH1A1POLBNAMPTHDAC3 | |
| SCHEMBL6773439 | 0.82 | TRPV1 (0.44) | HDAC3HDAC1TLR7HDAC2 | |
| SCHEMBL6780200 | 0.80 | ALDH1A1 (0.50) | TP53BP1ALDH1A1POLBNAMPTHDAC3 | |
| SCHEMBL6777932 | 0.78 | MAPT (0.43) | — | |
| SCHEMBL6098139 | 0.78 | DYRK1A (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100387597-C | Amido-substituted imidazopyridines | 3M INNOVATIVE PROPERTIES CO (US) | 2008-05-14 | — | — | CN | claimed |
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |