Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768483 | 0.90 | DRD3 (0.44) | POLBMAPK10MAPK14HTR1ADRD2 | |
| SCHEMBL6773439 | 0.87 | TRPV1 (0.44) | HDAC3HDAC1NPC1RAB9AHDAC2 | |
| SCHEMBL6773548 | 0.86 | HDAC3 (0.49) | HTR1ADRD2DRD4ADRA1DADRA1A | |
| SCHEMBL6098139 | 0.83 | DYRK1A (0.37) | — | |
| SCHEMBL6773542 | 0.83 | TP53BP1 (0.48) | POLBDRD2ADRA1ADRD3HDAC3 | |
| SCHEMBL5747384 | 0.83 | TLR7 (0.50) | POLBMAPK10MAPK14ADRA1DADRA1A | |
| SCHEMBL6772103 | 0.82 | MCHR1 (0.51) | DRD2DRD4DRD3TP53GAA | |
| SCHEMBL6769799 | 0.81 | MCHR1 (0.50) | DRD3HDAC3GAANAMPT | |
| SCHEMBL6773196 | 0.81 | ALDH1A1 (0.39) | HDAC1HDAC2 | |
| SCHEMBL6774104 | 0.80 | POLB (0.44) | POLBTP53HDAC3HDAC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |