Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4265760 | 0.77 | CYP11B2 (0.48) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL447619 | 0.75 | LMNA (0.44) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL2492332 | 0.73 | KMT2A (0.47) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL17926141 | 0.72 | MAOB (0.46) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL9481844 | 0.72 | ALOX5 (0.47) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL9481827 | 0.71 | ALOX5 (0.42) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL198499 | 0.69 | CYP1A2 (0.55) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL30454012 | 0.69 | CYP1A2 (0.55) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL24265435 | 0.69 | L3MBTL1 (0.46) | LMNAMAPTSMN1; SMN2L3MBTL1GABRG2 | |
| SCHEMBL2037015 | 0.69 | NUDT1 (0.47) | MAOBGAAMAPTMAOARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762197-B2 | FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1238975-A1 | DIFLUOROMETHYLTRIAZOLONE COMPOUNDS, USE OF THE SAME AND INTERMEDIATES FOR THE PRODUCTION THEREOF | Sumitomo Chemical Company, Limited (JP) | 2002-09-11 | — | — | EP | disclosed |