Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773386 | 0.95 | TP53BP1 (0.49) | ALDH1A1POLBRXFP1TP53BP1ABL1 | |
| SCHEMBL6773364 | 0.89 | RXFP1 (0.43) | ALDH1A1POLBRXFP1MAPTHDAC3 | |
| SCHEMBL6773842 | 0.84 | SMN1; SMN2 (0.50) | ALDH1A1POLBMEN1KMT2AMAPT | |
| SCHEMBL6772992 | 0.84 | HDAC3 (0.40) | ALDH1A1RXFP1MAPTNAMPTHDAC3 | |
| SCHEMBL6773218 | 0.83 | MCHR1 (0.47) | ALDH1A1POLBMAPTNAMPTHDAC3 | |
| SCHEMBL6772811 | 0.82 | ALDH1A1 (0.46) | ALDH1A1POLBTP53BP1ABL1BCR | |
| SCHEMBL6773253 | 0.81 | GAA (0.41) | ALDH1A1POLBABL1BCRMAPT | |
| SCHEMBL6773542 | 0.80 | TP53BP1 (0.48) | ALDH1A1POLBTP53BP1ABL1BCR | |
| SCHEMBL6780394 | 0.80 | TRPV1 (0.47) | MAPTHDAC3HDAC1TLR7 | |
| SCHEMBL6777601 | 0.79 | MEN1 (0.48) | MEN1KMT2ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |