Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773965 | 0.94 | BRD4 (0.44) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6773253 | 0.85 | GAA (0.41) | POLBKDM4E | |
| SCHEMBL6768729 | 0.84 | TLR7 (0.47) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6773364 | 0.83 | RXFP1 (0.43) | NPC1POLBKDM4E | |
| SCHEMBL6771355 | 0.83 | POLB (0.47) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6768482 | 0.82 | IDO1 (0.47) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6779087 | 0.82 | NOS3 (0.48) | RAB9AKMT2AMEN1POLBKDM4E | |
| SCHEMBL6775047 | 0.81 | TLR7 (0.44) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6780394 | 0.80 | TRPV1 (0.47) | — | |
| SCHEMBL6773356 | 0.79 | SMN1; SMN2 (0.48) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |