Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768482 | 0.83 | IDO1 (0.47) | SMN1; SMN2ALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL6774657 | 0.81 | MAPT (0.49) | SMN1; SMN2ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL6768729 | 0.81 | TLR7 (0.47) | SMN1; SMN2ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL6773364 | 0.80 | RXFP1 (0.43) | ALDH1A1NPC1HPGDMCHR1KDM4E | |
| SCHEMBL6774081 | 0.79 | RAB9A (0.44) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL6779087 | 0.79 | NOS3 (0.48) | ALDH1A1RAB9AHPGDKMT2AMEN1 | |
| SCHEMBL6773842 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL6773218 | 0.78 | MCHR1 (0.47) | ALDH1A1HPGDMCHR1KDM4EMAPT | |
| SCHEMBL6779944 | 0.77 | HDAC3 (0.48) | — | |
| SCHEMBL6780394 | 0.77 | TRPV1 (0.47) | MCHR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |