Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.61 |
| ▸ | CTSK | P43235 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4394779 | 0.80 | HDAC6 (0.51) | CTSSHDAC6HCRTR1HCRTR2 | |
| SCHEMBL29646334 | 0.75 | P2RX7 (0.58) | HDAC6ACKR3HCRTR1HCRTR2P2RX7 | |
| SCHEMBL7988780 | 0.75 | HDAC6 (0.58) | HDAC6ACKR3HCRTR1HCRTR2P2RX7 | |
| SCHEMBL1447540 | 0.75 | P2RX7 (0.58) | HDAC6ACKR3HCRTR1HCRTR2P2RX7 | |
| Hydrochloric Acid SCHEMBL7790006 | 0.72 | CAPN1 (0.52) | CTSSCTSKCAPN1ATMMEN1 | |
| Hydrochloric Acid SCHEMBL7790002 | 0.72 | CAPN1 (0.52) | CTSSCTSKCAPN1ATMMEN1 | |
| SCHEMBL4372942 | 0.72 | HDAC6 (0.51) | HDAC6ACKR3HCRTR1HCRTR2P2RX7 | |
| SCHEMBL1568625 | 0.71 | HDAC6 (0.57) | CTSSCTSKHDAC6ACKR3HCRTR1 | |
| SCHEMBL5904488 | 0.71 | HDAC6 (0.57) | HDAC6MEN1KMT2A | |
| SCHEMBL4384318 | 0.71 | HDAC6 (0.48) | HDAC6ACKR3HCRTR1HCRTR2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699853-B2 | PROTECTING USEFUL PLANTS AGAINST THE UNDESIRABLE ACTION OF HARMFUL INSECTS, ACARIDS AND NEMATODES, | HOECHST SCHERING AGREVO GMBH (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030162812-A1 | 4-haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, processes for their preparation, compositions comprising them, and their use as pesticides | HARMSEN SVEN (DE) | 2003-08-28 | — | — | US | disclosed |
| US-6521610-B2 | For controlling harmful insects, acarina and nematodes | HOECHST SCHERING AGREVO GMBH (DE) | 2003-02-18 | — | — | US | disclosed |
| US-20020013326-A1 | 4-Haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclyl-pyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | TIEBES JORG (DE) | 2002-01-31 | — | — | US | disclosed |
| US-6239160-B1 | 4-haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclylpyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | HOECHST SCHERING AGREVO GMBH (DE) | 2001-05-29 | — | — | US | disclosed |
| WO-2000035285-A1 | 4-HALOALKYL-3-HETEROCYCLYLPYRIDINES AND 4-HALOALKYL-5-HETEROCYCLYL-PYRIMIDINES AND THEIR USE AS REPELLENTS | AVENTIS CROPSCIENCE GMBH (DE) | 2000-06-22 | — | — | WO | disclosed |
| EP-0991648-A1 | 4-HALOALKYL-3- HETEROCYCLYLPYRIDINES AND 4-HALOALKYL -5-HETEROCYCLYLPYRIDINES, METHOD FOR THE PRODUCTION THEREOF, AGENTS CONTAINING THE SAME AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998057969-A1 | 4-HALOALKYL-3- HETEROCYCLYLPYRIDINES AND 4-HALOALKYL -5-HETEROCYCLYLPYRIDINES, METHOD FOR THE PRODUCTION THEREOF, AGENTS CONTAINING THE SAME AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1998-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162812-A1 | 4-haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, processes for their preparation, compositions comprising them, and their use as pesticides | DDT, HCK, HPD | CTSS 1339/4885CTSK 994/4885HDAC6 2389/4885 |
| US-20020013326-A1 | 4-Haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclyl-pyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | DDT, HAX1, HDHD5 | CTSS 1026/4885CTSK 1420/4885HDAC6 3209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.