Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22312249 | 0.85 | KMT2A (0.52) | NPC1KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL1019064 | 0.81 | PPIB (0.52) | L3MBTL1MLYCDMAOBRAB9AKMT2A | |
| SCHEMBL6785142 | 0.81 | PLA2G4B (0.50) | MLYCDNPC1RAB9AALOX5POLB | |
| SCHEMBL1016035 | 0.77 | ALDH1A1 (0.52) | LMNAL3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL19261529 | 0.75 | TSHR (0.58) | CNR2LMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL21480025 | 0.74 | NPC1 (0.46) | LMNANPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL2290221 | 0.74 | SMN1; SMN2 (0.51) | L3MBTL1NPC1RAB9AALOX5KMT2A | |
| SCHEMBL6789881 | 0.73 | FAAH (0.51) | FAAHPOLBKMT2AALDH1A1PKM | |
| SCHEMBL22073096 | 0.72 | ALDH1A1 (0.44) | L3MBTL1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL8387473 | 0.71 | ALOX5 (0.74) | MAOBALOX5NOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6710060-B2 | 4-hydroxypiperidine derivatives having antiarrhythmic activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-23 | — | — | US | disclosed |
| US-6642257-B2 | Fewer side-effects than do the conventional analgesics; 4-hydroxypiperidine derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2003-11-04 | — | — | US | disclosed |
| US-20020188006-A1 | 4-hydroxypiperidine derivatives having antiarrhythmic activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-12 | — | — | US | disclosed |
| US-20020049229-A1 | Agents for treating neuropathic pain | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-25 | — | — | US | disclosed |
| EP-1182193-A1 | REMEDIES FOR NEUROPATHIC PAIN | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-27 | — | — | EP | disclosed |
| EP-1182192-A1 | 4-HYDROXYPIPERIDINE DERIVATIVES HAVING ANTIARRHYTHMIC EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049229-A1 | Agents for treating neuropathic pain | OPRM1, OPRK1, OPRL1 | CNR2 8/4885LMNA 4829/4885L3MBTL1 3004/4885 |
| US-20020188006-A1 | 4-hydroxypiperidine derivatives having antiarrhythmic activity | SCN5A, RYR2, SCN1B | CNR2 1258/4885LMNA 337/4885L3MBTL1 500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.