Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 3/20 | 0.43 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.40 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893016 | 0.96 | CA4 (0.40) | CA4FAHD1CA1MEN1LDHA | |
| SCHEMBL22782 | 0.96 | — | — | |
| SCHEMBL9639951 | 0.96 | CA4 (0.46) | CA4FAHD1CA1MEN1LDHA | |
| SCHEMBL23592 | 0.96 | CA4 (0.36) | CA4FAHD1CA1 | |
| Water SCHEMBL3728022 | 0.92 | CA1 (0.33) | CA4FAHD1CA1 | |
| SCHEMBL8105624 | 0.92 | CA1 (0.33) | CA4FAHD1CA1 | |
| SCHEMBL7183669 | 0.92 | CA1 (0.33) | CA4FAHD1CA1 | |
| Lithium Ion SCHEMBL9249821 | 0.92 | CA1 (0.33) | CA4FAHD1CA1 | |
| SCHEMBL2353885 | 0.92 | CA1 (0.33) | CA4FAHD1CA1 | |
| Ammonia Solution, Strong SCHEMBL2338449 | 0.92 | CA1 (0.33) | CA4FAHD1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8980983-B2 | Highly flexible, halogen-free and fire-resistant thermoplastic cable mixtures | LANXESS DEUTSCHLAND GMBH (DE) | 2015-03-17 | — | — | US | claimed |
| EP-1655326-B1 | Crosslinked polymer foam sheet and process therefor | SEKISUI ALVEO AG (CH) | 2012-03-28 | — | — | EP | claimed |
| US-20120010346-A1 | HIGHLY FLEXIBLE, HALOGEN-FREE AND FIRE-RESISTANT THERMOPLASTIC CABLE MIXTURES | LANXESS DEUTSCHLAND GMBH (DE) | 2012-01-12 | — | — | US | claimed |
| EP-2315798-B1 | HIGHLY FLEXIBLE, HALOGEN-FREE AND FIRE-RESISTANT THERMOPLASTIC CABLE MIXTURES | LANXESS DEUTSCHLAND GMBH (DE) | 2011-12-28 | — | — | EP | claimed |
| EP-2189495-A1 | Highly flexible, halogen-free and flame-retardant thermoplastic cable mixtures | Lanxess Deutschland GmbH (DE) | 2010-05-26 | — | — | EP | claimed |
| US-20080103221-A1 | Crosslinked Polymer Foam Sheet and Process Therefor | SEKISUI VOLTEK, LLC | 2008-05-01 | — | — | US | claimed |
| WO-2006048333-A1 | CROSSLINKED POLYMER FOAM SHEET AND PROCESS THEREFOR | VOLTEK LLC (US) | 2006-05-11 | — | — | WO | claimed |
| EP-1655326-A1 | Crosslinked polymer foam sheet and process therefor | Alveo AG (CH) | 2006-05-10 | — | — | EP | claimed |
| US-6323269-B1 | CONVENIENT WAY OF INTRODUCING A BLOWING AGENT INTO A THERMOPLASTIC MATERIAL WHICH IS USED TO FORM FOAMED THERMOPLASTIC | IMERYS PIGMENTS, INC. | 2001-11-27 | — | — | US | claimed |
| EP-1064325-A1 | MINERAL CONTAINING THERMOPLASTIC GRANULES | Imerys Minerals Limited (GB) | 2001-01-03 | — | — | EP | claimed |
| US-5218027-A | Olefinic copolymer with carboxylic acid comonomer, elastomer, metal oxide hydrate and organopolysiloxane | MOTRILE INDUSTRIES, LTD. (CA) | 1993-06-08 | — | — | US | claimed |
| EP-0333514-B1 | LOW TOXICITY, FIRE RETARDANT THERMOPLASTIC MATERIAL | MORTILE INDUSTRIES LTD (CA) | 1993-05-19 | — | — | EP | claimed |
| EP-0482007-A4 | ENDOTHERMIC BLOWING AGENTS COMPOSITIONS AND APPLICATIONS | — | 1992-05-13 | — | — | EP | claimed |
| EP-0482007-A1 | ENDOTHERMIC BLOWING AGENTS COMPOSITIONS AND APPLICATIONS. | HUBER CORP J M (US) | 1992-04-29 | — | — | EP | claimed |
| US-5106534-A | Polycarboxylic acid and inorganic carbonate surface treated with component which prevents water absorption | J. M. HUBER CORPORATION (US) | 1992-04-21 | — | — | US | claimed |
| US-5045570-A | Additives are caused to concentrate at the surface of the foamed article | J. M. HUBER CORPORATION (US) | 1991-09-03 | — | — | US | claimed |
| US-5037580-A | Mixture of surface treated polycarboxylic acid and inorganic carbonate | J. M. HUBER CORPORATION (US) | 1991-08-06 | — | — | US | claimed |
| US-5009810-A | Mixture of polycarboxylic acid and inorganic carbonate surface treated with silane coupling agent, monoglycerides or stearic acid; foaming polymers | J. M. HUBER CORPORATION (US) | 1991-04-23 | — | — | US | claimed |
| WO-1990014384-A1 | ENDOTHERMIC BLOWING AGENTS COMPOSITIONS AND APPLICATIONS | J.M. HUBER CORPORATION (US) | 1990-11-29 | — | — | WO | claimed |
| EP-0333514-A1 | Low toxicity, fire retardant thermoplastic material | MORTILE INDUSTRIES LTD (CA) | 1989-09-20 | — | — | EP | claimed |