SCHEMBL678969

SCHEMBL678969

CCCC([C]=O)N1CCCC1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 19/20 0.38
SLC6A2 P23975 16/20 0.38
SLC6A4 P31645 12/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL678787 0.88 HRH3 (0.37) SLC6A3SLC6A2SLC6A4
SCHEMBL8904036 0.86 HRH3 (0.40) SLC6A3SLC6A2
SCHEMBL7290184 0.84 MAPT (0.36) SLC6A3SLC6A2
SCHEMBL678404 0.82 SLC6A2 (0.30) SLC6A3SLC6A2SLC6A4
SCHEMBL7717129 0.82 KMT2A (0.38)
SCHEMBL9660602 0.82 SIGMAR1 (0.36) SLC6A2SLC6A4
SCHEMBL7427732 0.80 FDPS (0.32)
SCHEMBL29100350 0.78 SLC6A3 (0.41) SLC6A3SLC6A2SLC6A4
SCHEMBL17393110 0.78 SLC6A3 (0.34) SLC6A3SLC6A2SLC6A4
SCHEMBL6039362 0.77 FDPS (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2160192-B1 ANTIMICROBIAL MATERIALS AND COATINGS COVIDIEN LP (US) 2018-03-28 EP disclosed
US-20170096391-A1 NOVEL LACTAMS BIOSIGNAL LIMITED (AU) 2017-04-06 US disclosed
US-9586901-B2 Lactams UNILEVER PLC (GB) 2017-03-07 US disclosed
US-8586618-B2 Furanone compounds and lactam analogues thereof BIOSIGNAL LIMITED (AU) 2013-11-19 US disclosed
EP-2177226-B1 Hydroxamate compositions COVIDIEN LP (US) 2013-09-18 EP disclosed
US-20130190377-A1 Novel Lactams BIOSIGNAL LIMITED (AU) 2013-07-25 US disclosed
US-8425972-B2 Antimicrobial materials and coatings COVIDIEN LP (US) 2013-04-23 US disclosed
EP-2564859-A1 Hydroxamate compositions Covidien LP (US) 2013-03-06 EP disclosed
US-8153741-B2 Furanone copolymers TYCO HEALTHCARE GROUP LP (US) 2012-04-10 US disclosed
US-8071691-B2 Furanone endcapped polymers TYCO HEALTHCARE GROUP LP (US) 2011-12-06 US disclosed
WO-2002013956-A1 MEMBRANES AND METHOD OF MANUFACTURE THEREOF GRADIPORE LIMITED (AU) 2002-02-21 WO disclosed
WO-2002000639-A1 SYNTHESIS OF CYCLIC COMPOUNDS UNISEARCH LIMITED (AU) 2002-01-03 WO disclosed
WO-2001076594-A1 ANTIMICROBIAL COATINGS UNISEARCH LIMITED (AU) 2001-10-18 WO disclosed
WO-2001068090-A1 MICROBIAL INHIBITORY COMPOSITIONS UNISEARCH LIMITED (AU) 2001-09-20 WO disclosed
US-20010020079-A1 Electrophoresis gels and cross-linking agents for their preparation THE UNIVERSITY OF MELBOURNE 2001-09-06 US disclosed
WO-2001043739-A1 INHIBITION OF TWO-COMPONENT SIGNAL TRANSDUCTION SYSTEMS UNISEARCH LIMITED (AU) 2001-06-21 WO disclosed
US-6197906-B1 ASSYMETRIC AGENTS SUCH AS (2-METHACRYLOYLOXYETHYL)ACRYLAMIDE, (2-ACRYLOYLOXYETHYL)METHACRYLAMIDE, AND (N-METHYL-N-ACRYLOYLAMINO)ETHYL METHACRYLATE THE UNIVERSITY OF MELBOURNE (AU) 2001-03-06 US disclosed
EP-0920412-A4 ELECTROPHORESIS GELS AND CROSS-LINKING AGENTS FOR THEIR PREPARATION UNIV MELBOURNE (AU) 2000-08-02 EP disclosed
EP-0920412-A1 ELECTROPHORESIS GELS AND CROSS-LINKING AGENTS FOR THEIR PREPARATION THE UNIVERSITY OF MELBOURNE (AU) 1999-06-09 EP disclosed
WO-1998001419-A1 ELECTROPHORESIS GELS AND CROSS-LINKING AGENTS FOR THEIR PREPARATION THE UNIVERSITY OF MELBOURNE (AU) 1998-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130190377-A1 Novel Lactams SULT1E1, PGLS, Q6ZSR9 SLC6A3 4395/4885SLC6A2 4441/4885SLC6A4 4658/4885
US-20170096391-A1 NOVEL LACTAMS SULT1E1, PGLS, Q6ZSR9 SLC6A3 4395/4885SLC6A2 4441/4885SLC6A4 4658/4885
US-20010020079-A1 Electrophoresis gels and cross-linking agents for their preparation MACF1, ZYX, F12 SLC6A3 4884/4885SLC6A2 4848/4885SLC6A4 4868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.