SCHEMBL679628

SCHEMBL679628

BrC(Br)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
MAPK1 P28482 1/20 0.50
CHRNB2 P17787 1/20 0.50
CHRNA4 P43681 1/20 0.50
ACP3 P15309 2/20 0.46
PTGS2 P35354 1/20 0.46
CYP3A4 P08684 3/20 0.43
TAAR1 Q96RJ0 2/20 0.43
CYP1A2 P05177 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MMP3 P08254 1/20 0.43
BCL2L1 Q07817 1/20 0.43
CYP2D6 P10635 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
CYP17A1 P05093 1/20 0.39
PTPN1 P18031 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL23358395 0.92 ALDH1A1 (0.53) ALDH1A1MAPK1CHRNB2CHRNA4ACP3
SCHEMBL5395302 0.88 CHRNB2 (0.35) ALDH1A1MAPK1CHRNB2CHRNA4ACP3
SCHEMBL29791940 0.87 ALDH1A1 (0.46) ALDH1A1MAPK1CHRNB2CHRNA4ACP3
SCHEMBL11218980 0.83 ALDH1A1 (0.50) ALDH1A1MAPK1CHRNB2CHRNA4ACP3
SCHEMBL150507 0.82
SCHEMBL8721667 0.81 CHRNB2 (0.54) ALDH1A1MAPK1CHRNB2CHRNA4ACP3
SCHEMBL6479076 0.79 PTGS2 (0.54) ALDH1A1MAPK1CHRNB2CHRNA4ACP3
SCHEMBL1764658 0.78 ESR1 (0.32) CYP3A4CYP1A2TDP1CYP2D6SLC6A2
SCHEMBL12880591 0.78 CHRNB2 (0.50) ALDH1A1MAPK1CHRNB2CHRNA4ACP3
SCHEMBL1538950 0.77 MAOA (0.44) ALDH1A1MAPK1CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344586-A Ion covalent organic polymer material and preparation method and application thereof 河北工程大学 2024-07-16 CN claimed
CN-115572371-B Preparation method of ionic porous polymer material and application of essential oil in adsorption and diterpene removal 杭州师范大学 2024-06-25 CN claimed
CN-118056852-A Carbazolyl porous organic framework material and preparation method and application thereof 右江民族医学院 2024-05-21 CN claimed
CN-116277696-B Multilayer heat-insulating pipe and production process thereof 河北乾海管道制造有限公司 2023-09-22 CN claimed
CN-116463693-A Treatment method for improving stability of semiconductor lead frame plating layer 崇辉半导体(江门)有限公司 2023-07-21 CN claimed
CN-116463697-A Surface oxidation-resistant corrosion-resistant coating treatment process for semiconductor lead frame 崇辉半导体(江门)有限公司 2023-07-21 CN claimed
CN-116277696-A Multilayer heat-insulating pipe and production process thereof 河北乾海管道制造有限公司 2023-06-23 CN claimed
CN-116284524-A Super-crosslinked porous polyionic liquid with high ionic liquid content, preparation method and application 合肥学院 2023-06-23 CN claimed
CN-113278054-B Cyclic peptide combined with new coronavirus RBD site as well as preparation method and application thereof 安徽大学 2023-03-24 CN claimed
CN-115572371-A Preparation method of ionic porous polymer material and application of essential oil in adsorption and terpene removal 杭州师范大学 2023-01-06 CN claimed
CN-113755475-A ACE2 cyclopeptide mimic and application thereof in inhibiting new coronavirus 西南医科大学附属中医医院 2021-12-07 CN claimed
CN-108358997-A A kind of stabilization polypeptide that intracellular that modifying construction of strategy using double sulfosalts is reversible 北京大学深圳研究生院 2018-08-03 CN claimed
US-20250188151-A1 C-JUN ANTAGONIST PEPTIDES THE UNIVERSITY OF BATH (GB) 2025-06-12 US disclosed
CN-119948079-A Multifunctional vinyl resin, method for producing the same, composition and cured product 日铁化学材料株式会社 2025-05-06 CN disclosed
WO-2025073982-A1 METHOD OF INTRACELLULAR PEPTIDE LIGATION THE UNIVERSITY OF BATH (GB) 2025-04-10 WO disclosed
CN-119604586-A Resin composition and cured product 日铁化学材料株式会社 2025-03-11 CN disclosed
US-4675355-A REACTIVE AMINE-CONTAINING NITROSO COMPOUND AND AN HALOGENATED ALKYLBENZENE TO IMPROVE GREEN STRENGTH; TIRES BRIDGESTONE CORPORATION (JP) 1987-06-23 US disclosed
US-4015995-A CATALYST COMPRISING ACID-RELEASING COMPOUND AND A BASE CHEVRON RESEARCH COMPANY (US) 1977-04-05 US disclosed
US-3947471-A CHROMOGENIC SUMITOMO CHEMICAL COMPANY, LTD. (JA) 1976-03-30 US disclosed
US-3943084-A Method for delaying the setting of and acid-settable liquid in a terrestrial zone CHEVRON RESEARCH COMPANY (US) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250188151-A1 C-JUN ANTAGONIST PEPTIDES JUN, JUND, FOS ALDH1A1 4745/4885MAPK1 733/4885CHRNB2 2720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.