Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | STAT5B | P51692 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434524 | 0.85 | AKT1 (0.44) | NR1H4HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL23912387 | 0.85 | NR1H4 (0.46) | NR1H4HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7473118 | 0.84 | LTB4R2 (0.49) | NR1H4HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL4315970 | 0.83 | PTGES (0.54) | NR1H4HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL5906827 | 0.83 | CHRM2 (0.50) | NR1H4HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL19922245 | 0.83 | AKT1 (0.47) | NR1H4HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL16640701 | 0.81 | NR1H4 (0.38) | NR1H4HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL5906599 | 0.81 | AKT1 (0.42) | NR1H4HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL22042475 | 0.81 | TRPM8 (0.45) | NR1H4HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL28628157 | 0.80 | LTB4R2 (0.56) | NR1H4HDAC3HDAC1HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040101864-A1 | Chemical process | ATRAZENECA AB (SE) | 2004-05-27 | — | — | US | disclosed |
| EP-1320538-A2 | PROCESS FOR THE PREPARATION OF 5-PHENYLPENTANOYL-ALA-ARGL-ALA- 2-[3-AMINO-2-OXOPYRROLIDIN-1-YL]PROPIONYL - ALA-ARG-ALA-4-AMINOPHENYLACETAMIDE | AstraZeneca AB (SE) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002008247-A2 | PROCESS FOR THE PREPARATION OF 5-PHENYLPENTANOYL-ALA-ARGL-{2-[3-AMINO-2-OXOPYRROLIDIN-1-YL]PROPIONYL}-ALA-ARG-ALA-4-AMINOPHENYLACETAMIDE | ASTRAZENECA AB (SE) | 2002-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040101864-A1 | Chemical process | ASS1, SRM, SRMS | NR1H4 1700/4885CNR2 3240/4885HDAC3 2063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.