Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3151639 | 0.79 | SRC (0.41) | HTTNPSR1ALDH1A1ALOX15ALOX12 | |
| SCHEMBL6806730 | 0.79 | ALOX15 (0.35) | HTTNPSR1ALDH1A1ALOX15ALOX12 | |
| SCHEMBL6807015 | 0.78 | TAS1R3 (0.40) | HTTNPSR1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL12774634 | 0.76 | MMP8 (0.40) | HTTALDH1A1MEN1CYP1A2KMT2A | |
| SCHEMBL31318197 | 0.72 | ALOX15 (0.37) | HTTNPSR1ALDH1A1POLBALOX15 | |
| SCHEMBL6807017 | 0.71 | MMP8 (0.41) | ALDH1A1POLBMEN1CYP1A2KMT2A | |
| SCHEMBL12843367 | 0.69 | THRA (0.31) | — | |
| SCHEMBL5439558 | 0.66 | TSHR (0.39) | ALDH1A1POLBALOX15ALOX12MAPT | |
| SCHEMBL11419339 | 0.64 | ALDH1A1 (0.53) | ALDH1A1POLBALOX15MEN1KMT2A | |
| SCHEMBL11406535 | 0.64 | SMN1; SMN2 (0.48) | HTTALDH1A1MEN1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198797-A1 | Process for the preparation of herbicidal derivatives | MAETZKE THOMAS (CH) | 2004-10-07 | — | — | US | disclosed |
| EP-1183317-B1 | PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-09-17 | — | — | EP | disclosed |
| US-6552187-B1 | Cyclization condensation of arylmalonic acid diamides or arylmalonic acid monoamides with hydrazine derivatives forming substituted 3-hydroxy-4-aryl-5-oxopyrazolines; high yield and purity | SYNGENTA CROP PROTECTION, INC. | 2003-04-22 | — | — | US | disclosed |
| EP-1183317-A2 | PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES | Syngenta Participations AG (CH) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000078881-A2 | PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES | SYGENTA PARTICIPATIONS AG (CH) | 2000-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198797-A1 | Process for the preparation of herbicidal derivatives | CBR3, CBR1, CYC1 | HTT 2889/4885NPSR1 2395/4885ALDH1A1 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.