Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13900603 | 0.79 | POLB (0.47) | TSHRPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL7290305 | 0.79 | TSHR (0.49) | TSHRPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL8675172 | 0.78 | SIGMAR1 (0.52) | TSHRCYP1A2OPRK1 | |
| SCHEMBL7008509 | 0.76 | TSHR (0.48) | TSHRPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL4785593 | 0.75 | TSHR (0.52) | TSHRPOLBMEN1KMT2AALDH1A1 | |
| Benzene SCHEMBL27914804 | 0.75 | AOC3 (0.55) | TSHRPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL10697566 | 0.75 | TSHR (0.52) | TSHRPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL167715 | 0.75 | AOC3 (0.55) | TSHRPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL28896083 | 0.75 | SIGMAR1 (0.45) | TSHRPOLBMEN1KMT2AALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL4461727 | 0.73 | AOC3 (0.53) | TSHRPOLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040053983-A1 | 1, 2, 4-tribsubstituted benzenes as inhibitors of 15-lipoxygenase | BARVIAN NICOLE CHANTEL (US) | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053983-A1 | 1, 2, 4-tribsubstituted benzenes as inhibitors of 15-lipoxygenase | ALOX15, ALOX5, ALOX15B | TSHR 1794/4885POLB 1525/4885MEN1 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.