Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 3/20 | 0.36 |
| ▸ | GABRD | O14764 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497168 | 0.79 | THRB (0.54) | ALDH1A1CYP1A2THRBKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL28548595 | 0.77 | THRB (0.52) | ALDH1A1CYP1A2THRBKMT2AMEN1 | |
| SCHEMBL11037692 | 0.76 | ALDH1A1 (0.52) | ALDH1A1CYP1A2THRBKMT2AMEN1 | |
| SCHEMBL28500432 | 0.76 | ALDH1A1 (0.52) | ALDH1A1CYP1A2THRBKMT2AMEN1 | |
| SCHEMBL1406211 | 0.74 | LMNA (0.46) | ALDH1A1CYP1A2THRBKMT2AMEN1 | |
| SCHEMBL11620113 | 0.74 | LMNA (0.46) | ALDH1A1CYP1A2THRBKMT2AMEN1 | |
| SCHEMBL9586044 | 0.74 | CYP1A2 (0.74) | ALDH1A1CYP1A2THRBKMT2AMEN1 | |
| SCHEMBL1933286 | 0.74 | — | — | |
| SCHEMBL1521278 | 0.74 | HMGCR (0.43) | ALDH1A1CYP1A2THRBKMT2AMEN1 | |
| SCHEMBL2825360 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3558287-A2 | N-ACETYLDIAMINOBUTYRIC ACID-CONTAINING COMPOSITION | Bitop AG (DE) | 2019-10-30 | — | — | EP | claimed |
| CN-114806974-B | Salmonella strain and application thereof | 中国科学院微生物研究所 | 2023-08-08 | — | — | CN | disclosed |
| CN-112501102-B | Escherichia coli recombinant bacterium for efficiently producing tetrahydropyrimidine | 江南大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-114806974-A | Halomonas strain and application thereof | 中国科学院微生物研究所 | 2022-07-29 | — | — | CN | disclosed |
| EP-2970511-B1 | INSULIN-INCRETIN CONJUGATES | UNIV INDIANA RES & TECH CORP (US) | 2020-09-30 | — | — | EP | disclosed |
| US-10730923-B2 | Glucagon/GLP-1 receptor co-agonists | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2020-08-04 | — | — | US | disclosed |
| US-10696726-B2 | Insulin-incretin conjugates | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2020-06-30 | — | — | US | disclosed |
| US-10683334-B2 | Aqueously soluble and chemically stable glucagon peptides | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2020-06-16 | — | — | US | disclosed |
| EP-3206710-B1 | INCRETIN-INSULIN CONJUGATES | UNIV INDIANA RES & TECH CORP (US) | 2020-05-06 | — | — | EP | disclosed |
| US-20200030214-A1 | USE OF COMPATIBLE SOLUTES | MERCK PATENT GMBH (DE) | 2020-01-30 | — | — | US | disclosed |
| US-20100316586-A1 | STYLING AGENT FOR KERATIN FIBERS | HENKEL AG & CO. KGAA (DE) | 2010-12-16 | — | — | US | disclosed |
| WO-2010071807-A1 | AMIDE BASED GLUCAGON SUPERFAMILY PEPTIDE PRODRUGS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2010-06-24 | — | — | WO | disclosed |
| WO-2010011439-A2 | GIP-BASED MIXED AGONISTS FOR TREATMENT OF METABOLIC DISORDERS AND OBESITY | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2010-01-28 | — | — | WO | disclosed |
| WO-2009155258-A2 | GLUCAGON/GLP-1 RECEPTOR CO-AGONISTS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2009-12-23 | — | — | WO | disclosed |
| WO-2009155257-A1 | GLUCAGON ANALOGS EXHIBITING ENHANCED SOLUBILITY AND STABILITY PHYSIOLOGICAL PH BUFFERS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2009-12-23 | — | — | WO | disclosed |
| EP-2057185-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | Northern Antibiotics Oy (FI) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008017734-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS OY (FI) | 2008-02-14 | — | — | WO | disclosed |
| CN-1303991-C | Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivative process for preparing the same | WARNER LAMBERT CO (US) | 2007-03-14 | — | — | CN | disclosed |
| US-20050201955-A1 | Use of compatible solutes for inhibiting the release of ceramides | SUSONITY Commercial GmbH (DE) | 2005-09-15 | — | — | US | disclosed |
| CN-1301155-A | Stable pharmaceutical formulation of gamma-aminobutyric acid derivatives and process for preparing the same | WARNER LAMBERT CO (US) | 2001-06-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050201955-A1 | Use of compatible solutes for inhibiting the release of ceramides | CERT1, UGCG, CERS2 | ALDH1A1 3836/4885CYP1A2 4709/4885THRB 4877/4885 |
| US-20200030214-A1 | USE OF COMPATIBLE SOLUTES | SLC9A5, SLC9A1, SLC9A3 | ALDH1A1 1133/4885CYP1A2 4075/4885THRB 4881/4885 |
| US-10730923-B2 | Glucagon/GLP-1 receptor co-agonists | GLP1R, GCGR, GIPR | ALDH1A1 4327/4885CYP1A2 3113/4885THRB 70/4885 |
| US-10696726-B2 | Insulin-incretin conjugates | GLP1R, IAPP, GIPR | ALDH1A1 3209/4885CYP1A2 3053/4885THRB 163/4885 |
| US-10683334-B2 | Aqueously soluble and chemically stable glucagon peptides | IAPP, GLP1R, GCG | ALDH1A1 4258/4885CYP1A2 3698/4885THRB 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.