Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMAD3 | P84022 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | GLB1 | P16278 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5958386 | 0.92 | SMAD3 (0.36) | SMAD3ALDH1A1HPGDHSD17B10BRCA1 | |
| SCHEMBL29461682 | 0.87 | SMAD3 (0.40) | SMAD3ALDH1A1HPGDHSD17B10BRCA1 | |
| SCHEMBL235829 | 0.87 | SMAD3 (0.40) | SMAD3ALDH1A1HPGDHSD17B10BRCA1 | |
| SCHEMBL500740 | 0.85 | MAPT (0.33) | SMAD3ALDH1A1HPGDHSD17B10BRCA1 | |
| Cyanide SCHEMBL6533545 | 0.84 | SMAD3 (0.38) | SMAD3ALDH1A1HPGDHSD17B10BRCA1 | |
| SCHEMBL229962 | 0.84 | ALDH1A1 (0.43) | SMAD3ALDH1A1HPGDHSD17B10BRCA1 | |
| SCHEMBL3983885 | 0.81 | MAPT (0.39) | SMAD3ALDH1A1HPGDHSD17B10BRCA1 | |
| SCHEMBL6045753 | 0.80 | ALDH1A1 (0.47) | SMAD3ALDH1A1HPGDHSD17B10BRCA1 | |
| SCHEMBL231207 | 0.80 | ALDH1A1 (0.58) | SMAD3ALDH1A1HPGDHSD17B10BRCA1 | |
| SCHEMBL1022908 | 0.78 | SMAD3 (0.40) | SMAD3ALDH1A1HPGDHSD17B10BRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9110075-B2 | Compositions for analyzing proteins | MONOGRAM BIOSCIENCES, INC. (US) | 2015-08-18 | — | — | US | claimed |
| EP-0978569-B1 | METHOD OF DNA SEQUENCING | RIKAGAKU KENKYUSHO (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-6482938-B1 | Compounds having energy transfer function and method for DNA base sequencing by using the same | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2002-11-19 | — | — | US | disclosed |
| US-6365350-B1 | REACTING RIBONUCLEOTIDE 5'-TRIPHOSPHATES AND 3'-DEOXY NUCLEOTIDE TRIPHOSPHATES WITH RNA POLYMERASE AND DNA FRAGMENT CONTAINING A PROMOTER SEQUENCE FOR THE POLYMERASE, THEN SEPARATING THE TRANSCRIPTION PRODUCT AND SEQUENCING IT | THE INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH (JP) | 2002-04-02 | — | — | US | disclosed |
| US-6265569-B1 | HAS ALKYL LINKER INCLUDING DOUBLE OR TRIPLE BOND WHICH ATTACHES FLUORESCENT MOLECULE TO NUCLEOTIDE; FOR TERMINATORS IN DNA SEQUENCING USING RNA POLYMERASES | THE INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1046648-A1 | 3'-DEOXYRIBONUCLEOTIDE DERIVATIVES | THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH (JP) | 2000-10-25 | — | — | EP | disclosed |
| EP-0978569-A1 | METHOD OF DNA SEQUENCING | THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH (JP) | 2000-02-09 | — | — | EP | disclosed |
| EP-0967219-A1 | COMPOUNDS HAVING ENERGY TRANSFER FUNCTION AND METHOD FOR DNA BASE SEQUENCING BY USING THE SAME | THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH (JP) | 1999-12-29 | — | — | EP | disclosed |